Influence of Vertical Implant Position on Marginal Bone Loss in Cases With Thin Phenotype

NCT07483086 | Recruiting DMC

• 2 other identifiers: PER 00-6-3-24511906268
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if vertical position of the dental implant will affect the bone around the implant in place of a missing tooth that happens to be bounded by two natural teeth. It will also measure esthetics and patient satisfaction. The main questions it aims to answer are: Does vertical implant position below the crest of the bone lead to less marginal bone loss? Will it affect implant survival as well as quality of soft tissue, esthetics and patient satisfaction? Participants will: Have an implant placed at the bone level or 2 mm below the bone level Visit the clinic once every 3 months for checkups, radiographs, and readings

Conditions

Vertical Implant Position; Delayed Implant Placement With Immediate Loading; Tooth Loss / Rehabilitation

Keywords

Vertical position; subcrestal; crestal; delayed implant placement with immediate loading; vertical dental implant position

Outcome Measures

Primary Outcomes (1)

• Marginal bone loss (crestal bone loss)

  measured linearly in mm by comparing periapical radiographs

  Assessment at baseline, 3 months post-operative, 6 months post-operative, 9 months post-operative and 12 months post-operative

Secondary Outcomes (8)

• Midfacial recession

  0, 3, 6, 9, 12 months post-operative

• Pink Esthetic Score (PES)

  baseline, 3, 6, 9, 12 months post-operative

• Gingival thickness

  baseline, 3, 6, 9, 12 months post-operative

• Implant survival

  12 months post-operative

• Post-operative patient satisfaction

  12 months post-operative

Study Arms (2)

Delayed implant with immediate temporization placed 2 mm subcrestal level

EXPERIMENTAL

Procedure: Delayed implant with immediate temporization placed 2 mm subcrestal level

Delayed implant with immediate temporization placed at crestal bone level

ACTIVE COMPARATOR

Procedure: Delayed implant with immediate temporization placed at the crestal level

Interventions

Delayed implant with immediate temporization placed 2 mm subcrestal level PROCEDURE

2 mm subcrestal placement

Delayed implant with immediate temporization placed 2 mm subcrestal level

Delayed implant with immediate temporization placed at the crestal level PROCEDURE

crestal level placement

Delayed implant with immediate temporization placed at crestal bone level

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with single missing upper anterior or premolar teeth
• Patients with minimum buccolingual width of 6 mm and mesiodistal width of 6 mm
• Patients with thin soft tissue phenotype
• Patients with healthy systemic conditions.
• Patients older than 18 years.
• Good oral hygiene.
• Cooperative patients who accept a one-year follow-up period.
• Patients who consent to being part of the study (sign an informed consent form).
• Adequate inter-arch space for implant placement.
• Favorable occlusion (no traumatic occlusion).
• Absence of allergy to the prescribed medications.

You may not qualify if:

• Patients with inadequate bone volume and/ or quality
• Patients with local root remnants
• Patients with inadequate wound healing
• Patients with signs of acute infection related to the area of interest.
• Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits (Lobbezoo et al., 2006).
• Heavy smokers (more than 10 cigarettes per day) (Lambert, Morris and Ochi, 2000).
• Metabolic diseases such as diabetes or hyperthyroidism as well as systemic medications such as chemotherapy or bisphosphonates
• Pregnant or nursing women.
• Uncooperative patients.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Tooth Loss

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Tooth Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: March 16, 2026
• First Posted: March 19, 2026
• Study Start: January 16, 2025
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: April 2, 2026

Record last verified: 2025-08

Locations

EG (1)