Erector Spinae Plane Block for Pain Control After Open Abdominal Surgery

NCT07479069 | Active Not Recruiting

• 1 other identifier: FMH-15/12/2025-IRB-1840
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

his randomized controlled trial aims to evaluate the efficacy of the bilateral erector spinae plane (ESP) block in reducing postoperative opioid consumption in patients undergoing open abdominal surgeries under general anesthesia

Conditions

Open Abdominal Surgery; Postoperative Pain

Keywords

Erector Spinae Block

Outcome Measures

Primary Outcomes (1)

• Postoperative Opioid Consumption

  Assessed by the percentage of patients requiring rescue opioid analgesia. The need for rescue analgesia is determined by a Visual Analogue Score (VAS) greater than five

  Within the first 24 hours after surgery

Study Arms (2)

Control Group

ACTIVE COMPARATOR

Patients receiving standard pain control treatment. Postoperatively, patients receive 1000 mg of IV paracetamol every 6 hours. If a patient reports a Visual Analogue Score (VAS) exceeding five, they will receive rescue analgesia consisting of nalbuphine 4mg

Drug: Standard Postoperative Analgesia

Erector Spinae Block Group

EXPERIMENTAL

Patients receiving bilateral ESP block in addition to standard pain control treatment

Procedure: Bilateral Erector Spinae Plane (ESP) Block; Drug: Standard Postoperative Analgesia

Interventions

Bilateral Erector Spinae Plane (ESP) Block PROCEDURE

Administered after the induction of general anesthesia and before the surgical incision. Local anesthetic (0.25% ropivacaine or 0.25% bupivacaine) will be injected for a total of 20-40 mL

Erector Spinae Block Group

Standard Postoperative Analgesia DRUG

Patients receive 1000 mg of IV paracetamol every 6 hours postoperatively. If a patient experiences a Visual Analogue Score (VAS) of more than five at any time, they receive rescue analgesia in the form of nalbuphine 4mg

Control Group; Erector Spinae Block Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American Society of Anesthesiology (ASA) stage I-II.
• Scheduled for abdominal surgery due to any indication.

You may not qualify if:

• History of Diabetes
• History of neuropathic diseases
• History of gastrointestinal bleeding, peptic ulcer, or inflammatory bowel disease
• History of long-term nonsteroidal anti-inflammatory
• History of chronic opioid analgesic use
• History of severe hepatic or renal failure

Sponsors & Collaborators

• Fatima Memorial Hospital: lead

Study Sites (1)

Department of Anesthesia, Fatima Memorial Hospital

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Parapsychology; Dental Occlusion

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Behavioral Sciences; Behavioral Disciplines and Activities; Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 13, 2026
• First Posted: March 18, 2026
• Study Start: October 1, 2025
• Primary Completion: March 31, 2026
• Study Completion: March 31, 2026
• Last Updated: March 18, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)