The Effect of Mindfulness-Based Nursing Interventions Applied to Hemodialysis Patients on Psychological Well-Being and Treatment Adherence

NCT07471828 | Completed

• 1 other identifier: KA25/443
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic kidney disease (CKD) and its treatment with hemodialysis pose significant challenges to patients' psychological well-being and adherence to complex treatment regimens. This randomized controlled trial investigated the effects of nurse-led, mindfulness-based interventions on psychological well-being and treatment adherence in patients undergoing hemodialysis. Eighty patients from a single dialysis center in Türkiye were randomly assigned to either an intervention group (n = 40) receiving six weekly mindfulness sessions or a control group (n = 40) receiving routine care. Data were collected using the Mindful Attention Awareness Scale (MAAS), the Psychological Well-Being Scale (PWB), and the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ) at baseline and post-intervention. Mixed-design analyses revealed significant improvements in mindfulness, psychological well-being, and all subscales of treatment adherence-including hemodialysis attendance, medication adherence, fluid management, and dietary compliance-in the intervention group compared to the control group (p \< 0.001). Moderate to large effect sizes (Cohen's d = 0.36-1.70) indicate clinically meaningful changes. Pearson correlation analysis demonstrated a positive association between psychological well-being and treatment adherence (r = 0.302, p \< 0.01). These findings suggest that structured, nurse-delivered mindfulness programs can simultaneously enhance psychosocial outcomes and adherence behaviors in hemodialysis patients. Integrating mindfulness-based interventions into routine nursing care may provide dual benefits by promoting emotional well-being and supporting self-regulated adherence to treatment regimens. Future research should explore long-term effects, broader patient populations, and the interplay between mindfulness, self-efficacy, and other psychosocial variables to further inform patient-centered hemodialysis care.

Conditions

Hemodialysis; Chronic Kidney Disease

Keywords

Mindfulness; Hemodialysis; Psychological Well-Being; Treatment Adherence

Outcome Measures

Primary Outcomes (3)

• Mindful Attention Awareness Scale (MAAS)

  15-item scale scored on a 6-point Likert scale. Scores range from 15 to 90; higher scores indicate higher mindfulness.

  6 weeks from baseline

• Psychological Well-Being Scale (PWBS)

  8-item scale scored on a 7-point Likert scale. Total scores range from 8 to 56; higher scores indicate higher psychological well-being.

  6 weeks from baseline

• End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ)

  9-item questionnaire assessing hemodialysis participation, medication adherence, fluid adherence, and diet adherence. Total scores range from 0 to 1200; higher scores indicate better adherence.

  6 weeks from baseline

Study Arms (2)

The Effect of Mindfulness-Based Nursing Interventions on Psychological Well-Being and Treatment Adhe

EXPERIMENTAL

Behavioral intervention, Six weekly sessions of mindfulness-based nursing interventions delivered to hemodialysis patients to improve psychological well-being and treatment adherence.

Other: The intervention group received mindfulness-based nursing interventions for six weeks

The control group

NO INTERVENTION

The control group continued to receive routine dialysis treatment and did not receive any additional education during the study period. Data collection instruments were administered at baseline and at the end of the study. After completion of the research, the educational content was shared with control group participants upon request.

Interventions

The intervention group received mindfulness-based nursing interventions for six weeks OTHER

The intervention group will receive mindfulness-based nursing interventions for 6 weeks, with one session per week averaging 1 hour.

Also known as: mindfulness

The Effect of Mindfulness-Based Nursing Interventions on Psychological Well-Being and Treatment Adhe

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Voluntarily agreed to participate in the study
• Receiving hemodialysis treatment for more than six months
• Literate
• years of age or older

You may not qualify if:

• Diagnosed severe psychiatric disorder according to DSM-5 criteria
• Auditory, visual, or cognitive impairments that could hinder participation in the educational process
• Withdrawal Criteria:
• Deterioration in general health status
• Participant's request to discontinue participation

Sponsors & Collaborators

• Baskent University: lead

Study Sites (1)

Baskent University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Psychological Well-Being; Treatment Adherence and Compliance

Interventions

Mindfulness

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Personal Satisfaction; Behavior; Health Behavior

Intervention Hierarchy (Ancestors)

Cognitive Behavioral Therapy; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: yok
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Model Details: Prior to the study, participants were informed in detail about the research, and both written and verbal informed consent were obtained. The principal investigator completed the relevant certification program before implementing the intervention. The intervention group received mindfulness-based nursing interventions for six weeks, consisting of one session per week, each lasting approximately one hour. One week after the completion of the intervention, post-test data were collected through face-to-face interviews using the data collection forms. The control group continued to receive routine dialysis treatment and did not receive any additional education during the study period. Data collection instruments were administered at baseline and at the end of the study. After completion of the research, the educational content was shared with control group participants upon request.

Study Record Dates

• First Submitted: March 3, 2026
• First Posted: March 13, 2026
• Study Start: December 11, 2025
• Primary Completion: January 26, 2026
• Study Completion: January 26, 2026
• Last Updated: March 13, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)