Impact of Cardiac Rehabilitation on Patient Outcomes

NCT07468955 | Completed

• 1 other identifier: KSBU- 2023/10-13
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

Objective: This study aimed to retrospectively evaluate the impact of cardiac rehabilitation (CR) on functional capacity, depressive symptoms, health-related quality of life, and sleep quality in patients with heart disease. Methods: A retrospective analysis was conducted on patients who participated in a structured CR program. Clinical records were reviewed to compare pre- and post-rehabilitation outcomes. Functional capacity was assessed using the 6-Minute Walk Test (6MWT), while depressive symptoms, health-related quality of life, and sleep quality were evaluated using the Beck Depression Inventory (BDI), the Short Form-36 (SF-36), and the Pittsburgh Sleep Quality Index (PSQI), respectively.

Conditions

Coronary Artery Disease; Coronary Heart Disease

Outcome Measures

Primary Outcomes (4)

• Functional Capacity

  unctional capacity is assessed using the 6-Minute Walk Test (6MWT). The distance walked in 6 minutes is recorded in meters. An increase in distance indicates improved functional exercise capacity.

  Baseline and post-intervention (6 week later)

• Change in Depressive Symptom

  Assessed using the Beck Depression Inventory (BDI). The BDI is a 21-item self-report scale. Scores range from 0 to 63, where higher scores indicate more severe depressive symptoms.

  Baseline and post-intervention (6 week later)

• Change in Quality of Life

  Assessed using the Short Form-36 (SF-36) Health Survey. It consists of 36 items covering 8 dimensions of health. Scores range from 0 to 100 for each subscale, with higher scores representing better health status.

  Baseline and post-intervention (6 week later)

• Change in Sleep Quality

  Assessed using the Pittsburgh Sleep Quality Index (PSQI). The PSQI consists of 19 individual items generating 7 component scores. The global score ranges from 0 to 21; higher scores indicate poorer sleep quality (scores \>5 suggest significant sleep disturbance).

  Baseline and post-intervention (6 week later)

Study Arms (1)

Cardiac Rehabilitation Group

EXPERIMENTAL

Patients in this group participated in a structured, multidisciplinary cardiac rehabilitation program. The intervention included individualized aerobic exercise training, resistance exercises, patient education, and psychosocial counseling.

Other: Exercise Based Cardiac Rehabilitation

Interventions

Exercise Based Cardiac Rehabilitation OTHER

The intervention consists of a structured, exercise-based cardiac rehabilitation (CR) program. The exercise protocol was tailored to each patient's clinical status and typically included aerobic endurance training complemented by resistance training for major muscle groups. Each session lasted approximately 40-60 minutes, consisting of a 10-minute warm-up, 20-40 minutes of moderate-intensity aerobic activity or high-intensity interval training (1:1 ratio), and a 10-minute cool-down period.

Cardiac Rehabilitation Group

Eligibility Criteria

• Age: 30 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients diagnosed with coronary artery disease (CAD), status post-myocardial infarction (MI), stable angina, or those who have undergone cardiac surgery
• Availability of complete pre- and post-rehabilitation clinical records, including 6-Minute Walk Test (6MWT), BDI, SF-36, and PSQI scores.
• Patients classified as stable by a cardiologist prior to the initiation of the exercise program.

You may not qualify if:

• Presence of severe orthopedic, neurological, or musculoskeletal disorders that prevent the performance of the 6-Minute Walk Test or exercise training.
• Patients with severe cognitive impairment
• Unstable angina pectoris, uncontrolled arrhythmias, or advanced heart failure (NYHA Class IV) that contraindicates aerobic exercise.
• Patients who dropped out of the rehabilitation program before completion or had more than a 20% absence rate in sessions.
• Patients who underwent major non-cardiac surgery within the last 3 months.

Sponsors & Collaborators

• Kutahya Health Sciences University: lead

Study Sites (1)

Kutahya Şehir Hastanesi Yoncalı Yerleşkesi

Kütahya, Center, 43100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Coronary Artery Disease; Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assit. Prof.

Study Record Dates

• First Submitted: March 9, 2026
• First Posted: March 13, 2026
• Study Start: July 14, 2019
• Primary Completion: October 30, 2023
• Study Completion: March 8, 2026
• Last Updated: July 30, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)