Placental Thickness -To-Fetal Weight Ratio as a Predictor of Adverse Pregnancy Outcome

NCT07467148 | Not Yet Recruiting

• 1 other identifier: P. Thickness to fetal weight
• Study Type: observational
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to evaluate the placental thickness-to-fetal weight ratio as a predictor of adverse pregnancy outcomes.

Conditions

Placental Thickness; PLACENTA VOLUME

Outcome Measures

Primary Outcomes (1)

• The rate of occurrence of adverse pregnancy outcomes, including IUGR, preterm birth, low birth weight, fetal distress, NICU admission, or perinatal mortality

  Correlation of placental thickness-to-fetal weight ratio with individual adverse pregnancy outcomes

  From aug 2026 to aug 2029

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Hospital

You may not qualify if:

• Multiple pregnancies (twins, triplets,etc.) Known congenital fetal anomalies Maternal chronic medical conditions affecting fetal growth (e.g pre-existing diabetes, hypertension, renal disease) Intrauterine fetal demise Inability or refusal to provide informed consent

Sponsors & Collaborators

• Radia Atef Elzokm: lead

Related Publications (1)

• 1.Burton GJ and Jauniaux E. The human placenta: new perspectives on its formation and function during early pregnancy. Proc Biol Sci. 2023;290(13):202-8. 2. Aye IL, Tong S, Charnock-Jones DS and Smith GC. The human placenta and its role in reproductive outcomes revisited. Physiol Rev. 2025;12(2):25-30. 3. Patel SY, Akileswaran C and Basu S. Early detection of high risk pregnancies using clinical and social data to improve health outcomes. npj Digit Public Health. 2026;10(1):3-10. 4. Wang X, Xiao F and Li J. Intrapartum ultrasound monitoring in second-stage Labor: Impact on delivery outcomes. J Radiat Res Appl Sci. 2025;18(4):105-10. 5. Farahbod F, Zarean E, Khanjani S, Moezzi M, Mohammadizadeh F and Shabanian S. Relationship between placental thickness, grading, and heterogeneity in fetal growth restriction in the third trimester of pregnancy by ultrasonography and pathology tests and their relationship with estimated fetal weight and neonatal outcome. Immunopathol Persa. 2023;10(2):39471-6. 6. Li H, Cheng W, Wen J, Peng J, Wu S, Zhao Y, et al. Clinical analysis of prophylactic uterine artery embolization combined with double balloon catheter for second-trimester pregnancy termination in cases of complete placenta previa: A retrospective study. Medicine. 2023;102(47):362-9. 7. Redline RW, Roberts DJ, Parast MM, Ernst LM, Morgan TK, Greene MF, et al. Placental pathology is necessary to understand common pregnancy complications and achieve an improved taxonomy of obstetrical disease. Am J Obstet Gynecol. 2023;228(2):187-202. 8. Manna C, Lacconi V, Rizzo G, De Lorenzo A and Massimiani M. Placental dysfunction in assisted reproductive pregnancies: perinatal, neonatal and adult life outcomes. Int J Mol Sci. 2022;23(2):659-62. 9. Chow LY, Williams EE, Patel D-S and Battersby C. Perinatal optimisation: the role of the multi-disciplinary team. OB-GYN 2025;22(1):25-30. 10. Lwanga SK, Lemeshow S. Sample size determination in health studies: a practical manual. Geneva: World H

  RESULT

Central Study Contacts

Radia Atef Elzokm, Resident doctor

CONTACT

01202170497; saraatef52222@gmail.com

Ahmed Mohamed Abbas, Professor

CONTACT

01003385183; Aahmedabbas@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assiut university

Study Record Dates

• First Submitted: March 8, 2026
• First Posted: March 12, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): August 1, 2029
• Study Completion (Estimated): December 1, 2029
• Last Updated: March 12, 2026

Record last verified: 2026-03