Lung Mechanics and Ventilation Efficiency in Robotic Surgery

NCT07467135 | Not Yet Recruiting

• 1 other identifier: TABED1-26-2262
• Study Type: observational
• Target: 65
• Locations: 0 countries
• Sites: N/A

Brief Summary

Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning. These intraoperative conditions may lead to cranial displacement of the diaphragm, reduced lung compliance, and increased airway pressures, potentially impairing respiratory mechanics and gas exchange. Previous studies have primarily evaluated respiratory mechanics during robotic surgery at single time points or within specific surgical procedures. However, dynamic changes occurring during critical phases of robotic surgery have rarely been evaluated prospectively. This prospective observational cohort study aims to evaluate phase-specific changes in lung mechanics and ventilation efficiency during robotic surgery. Key parameters including mechanical power (MP), ventilation efficiency index (VEI), static compliance, and driving pressure will be analyzed across predefined intraoperative phases.

Conditions

Robotic Surgery

Outcome Measures

Primary Outcomes (1)

• Ventilation Efficiency Index (VEI) change across robotic surgery phases

  Evaluation of VEI changes between predefined intraoperative phases.

  Intraoperative (T0-T4)

Secondary Outcomes (2)

• Mechanical Power Change

  intraoperative

• Static Lung Compliance Change

  intraoperative

Study Arms (1)

Robotic Surgery

Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation. Intraoperative respiratory mechanics and gas exchange parameters will be prospectively recorded during predefined phases of robotic surgery (T0-T4). Parameters include ventilatory settings, airway pressures, arterial blood gas values, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index. The study evaluates phase-specific changes in lung mechanics and ventilation efficiency during robotic surgical procedures.

Other: Intraoperative Mechanical Ventilation Monitoring

Interventions

Intraoperative Mechanical Ventilation Monitoring OTHER

Prospective recording of ventilatory parameters and respiratory mechanics during robotic surgery under general anesthesia. Measurements will be obtained at predefined surgical phases (after intubation, pneumoperitoneum initiation, steep Trendelenburg positioning, undocking, and before extubation). Recorded parameters include tidal volume, respiratory rate, peak airway pressure, plateau pressure, positive end-expiratory pressure, arterial blood gas measurements, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index.

Robotic Surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation. Robotic procedures from different surgical specialties such as urology, gynecology, and general surgery will be included.

You may qualify if:

• Age ≥ 18 years
• Patients undergoing robotic surgery
• General anesthesia with mechanical ventilation
• Written informed consent

You may not qualify if:

• Severe chronic pulmonary disease
• Refusal to participate
• Missing intraoperative ventilatory data

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assos. Prof

Study Record Dates

• First Submitted: March 8, 2026
• First Posted: March 12, 2026
• Study Start: March 20, 2026
• Primary Completion: April 1, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: March 12, 2026

Record last verified: 2026-03