Resistance Training on Depression and Quality of Life in Type 1 Diabetic Women

NCT07466186 | Not Yet Recruiting DMC

• 1 other identifier: Resistance Training
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Find out the effects of resistance training on depression, sleep quality, and quality of life in women with type 1 diabetes mellitus

Conditions

Type 1 Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

• Depression

  Depression will be assessed using the Beck Depression Inventory-II

  Baseline and 12 weeks later

Secondary Outcomes (2)

• Sleep quality

  At baseline and 12 weeks later

• Quality of life

  At baseline and after 12 weeks

Study Arms (2)

Resistance training group

ACTIVE COMPARATOR

Other: Resistance exercises; Other: Breathing exercises

Control group

ACTIVE COMPARATOR

Other: Breathing exercises

Interventions

Breathing exercises OTHER

The procedure will be first demonstrated and explained to each woman prior to the first session. Starting from a crook-lying position, participants will be guided to inhale through the nose for a count of four, hold their breath for another four counts, exhale slowly through the mouth over four counts, and then pause for an additional four counts before repeating the cycle.

Control group; Resistance training group

Resistance exercises OTHER

The program will include seven exercises targeting major muscle groups: chest press, triceps extension, and shoulder front raise for the upper limbs; back extensions and abdominal crunches for the trunk; and leg press, leg curl, and calf raise for the lower limbs.

Resistance training group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Diagnosis of type 1 diabetes for more than 5 years
• Unchanged insulin doses for no less than three months
• Good glycemic control, defined as glycated hemoglobin levels below 7%
• Minimal to moderate depressive symptoms
• Sleep quality impairment

You may not qualify if:

• Presence of other types of diabetes, unstable cardiopulmonary conditions, recent neurological or musculoskeletal problems affecting exercise, pregnancy, postmenopausal status, and the use of sedatives or antidepressants.

Sponsors & Collaborators

• Middle East University: lead

Study Sites (1)

Tanta University Hospital

Tanta, Egypt

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Interventions

Breathing Exercises

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Mohamed Saif

  National institute for Gerontology

  STUDY DIRECTOR

Central Study Contacts

Saher Elgayar, Ph.D

CONTACT

+201020429911; saherlotfy020@gmail.com

Mohammed Elhamrawy, Ph.D

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Physical Therapy

Study Record Dates

• First Submitted: March 8, 2026
• First Posted: March 12, 2026
• Study Start: March 18, 2026
• Primary Completion (Estimated): July 21, 2026
• Study Completion (Estimated): July 28, 2026
• Last Updated: March 12, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)