NCT07464379

Brief Summary

Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
32mo left

Started Jan 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress71%
Jan 2020Dec 2028

Study Start

First participant enrolled

January 1, 2020

Completed
6 years until next milestone

First Submitted

Initial submission to the registry

January 5, 2026

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 11, 2026

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2028

Last Updated

March 11, 2026

Status Verified

March 1, 2026

Enrollment Period

8 years

First QC Date

January 5, 2026

Last Update Submit

March 10, 2026

Conditions

Pregnancy-induced Hypertension

Outcome Measures

Primary Outcomes (1)

  • PIH

    the content of GPR18 type macrophages

    Early pregnancy：Weeks 1 to 12 (the first to third months of pregnancy) ；mid-pregnancy：Weeks 13 to 27 (the 4th to 6th month of pregnancy) ；post-delivery period：Weeks 28 to 40 (the 7th to 9th months of pregnancy)；the day of delivery。

Secondary Outcomes (3)

  • PIH

    delivery

  • PIH

    delivery

  • PIH

    delivery

Study Arms (2)

control group

Healthy pregnant women

Other: no Intervention

PIH group

Pregnancy-induced hypertension patients

Other: no Intervention

Interventions

no InterventionOTHER

observation

PIH groupcontrol group

Eligibility Criteria

Age20 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Healthy parturient women, women who have had miscarriages, patients with pregnancy-induced hypertension

You may qualify if:

  • \- Healthy pregnant women, patients with miscarriage, etc.

You may not qualify if:

  • Heart disease, infections, etc. in pregnant women Uncooperative patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Second Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, 325000, China

RECRUITING

MeSH Terms

Conditions

Hypertension, Pregnancy-Induced

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesHypertensionVascular DiseasesCardiovascular Diseases

Study Officials

  • Qian Wang

    The Second Affiliated Hospital of wenzhou Medical University Longwan Branch

    STUDY CHAIR

Central Study Contacts

Qian Wang, PHD

CONTACT

13587638653wqian84@163.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 5, 2026

First Posted

March 11, 2026

Study Start

January 1, 2020

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

December 31, 2028

Last Updated

March 11, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)