NCT07463976

Brief Summary

This study will use surveys within primary and secondary care to explore referral patterns and healthcare professional (HCP) decision-making and advice for haematological malignancies, identify inequalities, and establish best practice for CLL referrals and specialist support. The project will allow us to understand and 'map' variations in practice across the West Midlands region with regard to referrals for CLL from primary care physicians to haematology services in secondary care. Specific objectives are to:

  1. 1.Identify service variations by using surveys to assess differences in CLL service provision across primary and secondary care in the West Midlands
  2. 2.Investigate service variations by describing the key characteristics of responding primary care practices (practice size, number of GPs, Integrated Care Board (ICB) locality, deprivation quartile)
  3. 3.Propose strategies to improve equity that will enhanced patient outcomes and reduce inequalities in care for CLL patients, aiming to ensure consistent standards for referral and management across different care settings.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
130

participants targeted

Target at P50-P75 for all trials

Timeline
11mo left

Started Jul 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress9%
Jul 2026Jul 2027

First Submitted

Initial submission to the registry

February 26, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

March 11, 2026

Completed
4 months until next milestone

Study Start

First participant enrolled

July 1, 2026

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2027

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

1 year

First QC Date

February 26, 2026

Last Update Submit

April 8, 2026

Conditions

Chronic Lymphocytic LeukemiaHaematological Malignancy

Outcome Measures

Primary Outcomes (5)

  • Identify service variations

    Using surveys to assess differences in CLL service provision across primary and secondary care in the West Midlands

    12 months

  • Investigate service variations

    Investigate service variations by describing the key characteristics of responding primary care practices (practice size)

    12 months

  • Investigate service variations

    Investigate service variations by describing the key characteristics of responding primary care practices (number of GPs)

    12 months

  • Investigate service variations

    Investigate service variations by describing the key characteristics of responding primary care practices (Integrated Care Board (ICB) locality)

    12 months

  • Investigate service variations

    Investigate service variations by describing the key characteristics of responding primary care practices (deprivation quartile)

    12 months

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Surveys within primary and secondary care to explore referral patterns and healthcare professional (HCP) decision-making and advice for haematological malignancies, identify inequalities, and establish best practice for CLL referrals and specialist support. The project will allow us to understand and 'map' variations in practice across the West Midlands region with regard to referrals for CLL from primary care physicians to haematology services in secondary care.

You may qualify if:

  • Primary Care Provider
  • Clinical Nurse Specialist

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Royal Wolverhampton NHS Trust

Wolverhampton, WV10 0QP, United Kingdom

Location

MeSH Terms

Conditions

Leukemia, Lymphocytic, Chronic, B-CellHematologic Neoplasms

Condition Hierarchy (Ancestors)

Leukemia, B-CellLeukemia, LymphoidLeukemiaNeoplasms by Histologic TypeNeoplasmsHematologic DiseasesHemic and Lymphatic DiseasesLymphoproliferative DisordersLymphatic DiseasesImmunoproliferative DisordersImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsNeoplasms by Site

Study Officials

  • Shankara Paneesha

    University Hospitals Birmingham

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jen Edgecombe

CONTACT

01902 695065rwh-tr.ukchart@nhs.net

Lorraine Jacques

CONTACT

rwh-tr.sponsorshipofresearch@nhs.net

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 26, 2026

First Posted

March 11, 2026

Study Start

July 1, 2026

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

July 1, 2027

Last Updated

April 13, 2026

Record last verified: 2026-04

Locations

GB(1)