IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania
IDEAS for Hope: A Brief Telehealth Intervention to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania
1 other identifier
interventional
600
1 country
1
Brief Summary
In this project, the investigators will conduct a clinical trial to test the effectiveness and implementation of IDEAS for Hope, a 3-session telehealth counseling intervention delivered by nurses, to reduce suicidality and improve HIV care engagement among PLWH in Tanzania. The investigators will also examine mechanisms of change and implementation outcomes of the intervention, including cost-effectiveness, to disseminate a feasible, scalable, and sustainable intervention and implementation package to address a critical mental health comorbidity in HIV care.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2026
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 4, 2026
CompletedFirst Posted
Study publicly available on registry
March 9, 2026
CompletedStudy Start
First participant enrolled
August 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2031
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 30, 2031
March 12, 2026
March 1, 2026
4.5 years
March 4, 2026
March 10, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
Number of participants with Suicidal thinking
Self-report of actual thoughts of suicide in the last 30 days
6 months
Number of participants with a Suicidal plan
Self-report of plan to attempt suicide
6 months
Number of participants with Suicidal intent
Self-report of intent to attempt suicide
6 months
Number of participants with Suicide preparatory behavior
Self-report of preparatory behavior such as writing a suicide note or preparing materials to attempt suicide
6 months
Number of participants with Suicide attempt
Self-report of harming oneself with the intention of ending one's life
6 months
Number of participants with HIV care engagement
Single triangulated variable (yes/no) integrating self-reported antiretroviral medication adherence, HIV clinic attendance, and HIV viral load
6 months
Study Arms (2)
IDEAS for Hope
EXPERIMENTAL3-session, nurse-delivered, telehealth counseling intervention developmed by Knettel and colleagues
Brief Safety Planning
ACTIVE COMPARATORSingle session brief safety planning intervention (BSI) developed by Stanely \& Brown
Interventions
The IDEAS for Hope framework integrates Joiner's Interpersonal Theory to address stigma, burdensomeness, and other drivers of suicide risk and improve HIV care engagement. This includes theoretical grounding in Motivational Interviewing-enhanced safety planning (MI-SafeCope), stigma reduction, cognitive-behavioral therapy with adherence counseling (CBT-AD), and problem-solving therapy. MI-SafeCope improves coping for suicide risk by developing an individualized safety plan and facilitating social support. The integration of MI into standard safety planning goes beyond identifying coping strategies to facilitate values-driven improvement in health behavior and address the unique drivers of suicide risk among PLWH in Tanzania.
The single-session safety planning intervention (SPI) will be provided according to protocols developed by Stanley \& Brown. The SPI involves collaboratively creating a personalized, step-by-step plan to help individuals recognize warning signs, use coping strategies, seek support, and reduce access to means during a suicidal crisis.
Eligibility Criteria
You may qualify if:
- Adult
- Living with HIV
- Attending HIV care appointments
- Self-report experiencing thoughts of suicide in the last 30 days
You may not qualify if:
- Physically or cognitively unable to provide informed consent or complete study procedures
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Duke Universitylead
- RTI Internationalcollaborator
Study Sites (1)
Kilimanjaro Clinical Research Institute
Moshi, Tanzania
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Brandon A Knettel, Ph.D.
Duke University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 4, 2026
First Posted
March 9, 2026
Study Start
August 1, 2026
Primary Completion (Estimated)
January 31, 2031
Study Completion (Estimated)
June 30, 2031
Last Updated
March 12, 2026
Record last verified: 2026-03
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ANALYTIC CODE
Age, sex, ethnicity, socioeconomic status, depression symptoms, distress, suicide risk, suicide coping self-efficacy, hopelessness, reasons for living, anxiety symptoms, traumatic stress symptoms, impairment, resilience, social support, quality of life, study feedback, method and date of HIV diagnosis, antiretroviral therapy (ART) use and date of initiation, ART adherence, persistence, and retention, beliefs about ART, stigma, HIV knowledge, HIV acceptance.