FRONT Block for Quality of Recovery After Total Hip Arthroplasty

NCT07458360 | Recruiting

• 1 other identifier: FRONT BLOCK
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective randomized controlled trial evaluates the effect of ultrasound-guided unilateral Femoral Rami and Obturator Nerve Trunk (FRONT) block on postoperative quality of recovery in patients undergoing elective total hip arthroplasty.

Conditions

Osteoarthritis of the Hip; Postoperative Pain; Quality of Recovery

Outcome Measures

Primary Outcomes (1)

• Postoperative Quality of Recovery (QoR-15 Score)

  Postoperative quality of recovery will be assessed using the validated Quality of Recovery-15 (QoR-15) questionnaire. The total score ranges from 0 to 150, with higher scores indicating better recovery.

  24 hours after surgery

Secondary Outcomes (6)

• Quality of Recovery (QoR-15) Score at 48 Hours

  48 hours after surgery

• Postoperative Pain Intensity

  2, 6, 12, 24, and 48 hours after surgery

• Total Opioid Consumption

  0-24 hours after surgery

• Time to First Rescue Analgesia

  Within the first 24 hours after surgery

• Time to First Mobilization

  Within the first 48 hours after surgery

Study Arms (2)

FRONT Block Group

EXPERIMENTAL

Participants in this group will receive an ultrasound-guided unilateral Femoral Rami and Obturator Nerve Trunk (FRONT) block in addition to standardized multimodal postoperative analgesia.

Procedure: FRONT Block (Femoral Rami and Obturator Nerve Trunk Block); Procedure: Standard Multimodal Analgesia

Control Group

ACTIVE COMPARATOR

Participants in this group will receive standardized multimodal postoperative analgesia without FRONT block.

Procedure: Standard Multimodal Analgesia

Interventions

FRONT Block (Femoral Rami and Obturator Nerve Trunk Block) PROCEDURE

Ultrasound-guided unilateral FRONT block targeting the femoral rami and obturator nerve trunk will be performed

FRONT Block Group

Standard Multimodal Analgesia PROCEDURE

Standardized postoperative multimodal analgesia including intravenous paracetamol, nonsteroidal anti-inflammatory drugs, and rescue opioid analgesia as required.

Control Group; FRONT Block Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years
• Scheduled for total hip arthroplasty under spinal anesthesia
• American Society of Anesthesiologists (ASA) physical status I-III
• Ability to understand and complete the QoR-15 questionnaire
• Provided written informed consent

You may not qualify if:

• Refusal to participate
• Contraindication to spinal anesthesia or regional block
• Allergy to study medications
• Chronic opioid use (daily use for more than 3 months)
• Neurological or neuromuscular disorders affecting the lower extremities
• Infection at the injection site
• Coagulation disorders
• Cognitive impairment prevents questionnaire completion

Sponsors & Collaborators

• Konya Meram State Hospital: lead

Study Sites (1)

Betul Kozanhan

Konya, 42005, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Hip; Pain, Postoperative

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessments will be performed by independent researchers blinded to group allocation.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr.

Model Details: Participants will be randomized in a 1:1 ratio to receive either an ultrasound-guided unilateral FRONT block plus standard multimodal analgesia or standard multimodal analgesia alone. Outcomes will be compared between the two parallel groups.

Study Record Dates

• First Submitted: March 3, 2026
• First Posted: March 9, 2026
• Study Start: April 25, 2026
• Primary Completion (Estimated): June 5, 2026
• Study Completion (Estimated): July 5, 2026
• Last Updated: April 28, 2026

Record last verified: 2026-04

Locations

TU (1)