NCT07455877

Brief Summary

This current study will be designed to determine the effect of smart tablets hand training applications on hand functions and functional outcome in patients with stroke. Tablet-based hand function training app with smart tablet exercises: Patients in the study group will receive 20 min of smart tablet active hand therapy. Patients in the study and control group will receive 30 min of conventional physical therapy program. This program consists of neurodevelopmental facilitation techniques organized specifically for each patient, range of motion exercises, strengthening exercises . It includes the following functional tasks (reaching, grasping, lifting and placing objects).

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Mar 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress73%
Mar 2026Jul 2026

Study Start

First participant enrolled

March 1, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

March 3, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 6, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
24 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 25, 2026

Last Updated

March 9, 2026

Status Verified

February 1, 2026

Enrollment Period

4 months

First QC Date

March 3, 2026

Last Update Submit

March 5, 2026

Conditions

Chronic Stroke Patients

Keywords

strokeinteractive gameshand training

Outcome Measures

Primary Outcomes (2)

  • 1. Power and Pinch grip strength by hand dynamometer.

    from baseline to 6 weeks post intervention

  • Hand dexterity by Purdue peg board test.

    from baseline to 6 weeks post intervention

Study Arms (2)

Group A

EXPERIMENTAL

This group will receive smart tablet hand training applications for 20 minutes in addition to 30 minutes of conventional physical therapy program

Other: interactive gamesOther: conventional physical therapy

Group B

ACTIVE COMPARATOR

This group will receive the same conventional physical therapy program in the form of for prolonged stretch, active upper extremity exercises, balance, gait training and hand function

Other: conventional physical therapy

Interventions

interactive gamesOTHER

smart tablets hand training applications

Group A
conventional physical therapyOTHER

prolonged stretch, active upper extremity exercises, balance, gait training and hand function. Hand function training includes the following activities: turning cards, transfer cubes, grasping rubber ball, picking up coins

Group AGroup B

Eligibility Criteria

Age45 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Forty chronic ischemic stroke patients from both sexes.
  • Their ages will range from 45 - 65 years old.
  • Stroke duration between six months and two years.
  • Spasticity grade of the upper limb is from 1+to 2 according to the Modified Ashworth scale.
  • MMSE score \> 24 to ensure adequate cognitive function for following instructions.
  • Patients with at least 20° of wrist flexion/extension and at least 10° of finger flexion and extension of the paretic limb.
  • Brunnstrom stages ≥ 4 were included
  • Medically stable patients.

You may not qualify if:

  • Other neurological disorders (e.g.: Multiple sclerosis, Parkinsonism…etc).
  • Visual, auditory, and cognitive deficits.
  • Patients with psychological or sever cognitive disorders.
  • Patients with musculoskeletal problems (deformity or contracture).
  • Medically unstable and uncooperative patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (13)

  • Woytowicz, E. J., Rietschel, J. C., Goodman, R. N., Conroy, S. S., Sorkin, J. D., Whitall, J., & McCombe Waller, S. (2017). Determining Levels of Upper Extremity Movement Impairment by Applying a Cluster Analysis to the Fugl-Meyer Assessment of the Upper Extremity in Chronic Stroke. Archives of Physical Medicine and Rehabilitation, 98(3), 456-462.

    BACKGROUND

  • Ekstrand, E., Lexell, J., & Brogårdh, C. (2016). Pinch grip strength is a representative measure of muscle weakness in the upper extremity after stroke. Topics in Stroke Rehabilitation, 23(6), 400-405.

    BACKGROUND

  • Chien, W. tong, Chong, Y. yu, Tse, M. kei, Chien, C. woon, & Cheng, H. yu. (2020). Tablet-based hand training applications for upper-limb rehabilitation in subacute stroke patients: A systematic review and meta-analysis. Brain and Behavior, 10(8), 1-16.

    BACKGROUND

  • Bill, F., & Foundation, M. G. (2024). Articles Global , regional , and national burden of stroke and its risk factors , 1990 - 2021 : a systematic analysis for the Global Burden of Disease Study 2021. 973-1003.

    BACKGROUND

  • Rand, Debbie, Gabi Zeilig, and Rachel Kizony. "Rehab-let: touchscreen tablet for self-training impaired dexterity post stroke: study protocol for a pilot randomized controlled trial." Trials 16.1 (2015)

    BACKGROUND

  • Bertani, R., Melegari, C., De Cola, M. C., Bramanti, A., Bramanti, P., & Calabrò, R. S. (2017). Effects of smart tablet-assisted upper limb rehabilitation in stroke patients: a systematic review with meta-analysis. Neurological Sciences, 38(9), 1561-1569

    BACKGROUND

  • Olana, D. D., Abessa, T. G., Lamba, D., Triccas, L. T., & Bonnechere, B. (2025). Effect of virtual reality based upper limb training on activity of daily living and quality of life among stroke survivors: a systematic review and meta analysis. Journal of NeuroEngineering and Rehabilitation, 22, 92

    BACKGROUND

  • Recovery and prediction of dynamic precision grip force control after stroke. Stroke, 51(3), 944-951

    BACKGROUND

  • Pennati, G. V., Plantin, J., Carment, L., Roca, P., Baron, J.-C., Pavlova, E., Borg, J., & Lindberg, P. G. (2020).

    BACKGROUND

  • Veerbeek, J. M., Langbroek-Amersfoort, A. C., Van Wegen, E. E. H., Meskers, C. G. M., & Kwakkel, G. (2017). Effects of Smart tablet-Assisted Therapy for the Upper Limb after Stroke. Neurorehabilitation and Neural Repair, 31(2), 107-121.

    RESULT

  • Bertani, R., Melegari, C., De Cola, M. C., Bramanti, A., Bramanti, P., & Calabrò, R. S. (2017). Effects of smart tablet-assisted upper limb rehabilitation in stroke patients: a systematic review with meta-analysis. Neurological Sciences, 38(9), 1561-1569

    RESULT

  • Is the Combination of Smart tablet-Assisted Therapy and Transcranial Direct Current Stimulation Useful for Upper Limb Motor Recovery? A Systematic Review with Meta-Analysis. Healthcare (Switzerland), 12(3), 1-19

    RESULT

  • Bernal-Jiménez, J. J., Polonio-López, B., Sanz-García, A., Martín-Conty, J. L., Lerín-Calvo, A., Segura-Fragoso, A., Martín-Rodríguez, F., Cantero-Garlito, P. A., Corregidor-Sánchez, A. I., & Mordillo-Mateos, L. (2024)

    RESULT

Related Links

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of physical therapy cairo university

Study Record Dates

First Submitted

March 3, 2026

First Posted

March 6, 2026

Study Start

March 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

July 25, 2026

Last Updated

March 9, 2026

Record last verified: 2026-02