NCT07454330

Brief Summary

The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. The researchers will look at whether the combinations are practical and effective, and how they impact participants' quality of life.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P25-P50 for not_applicable cancer

Timeline
20mo left

Started Feb 2026

Geographic Reach
1 country

7 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress12%
Feb 2026Feb 2028

Study Start

First participant enrolled

February 27, 2026

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

March 2, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 6, 2026

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2028

Last Updated

May 1, 2026

Status Verified

April 1, 2026

Enrollment Period

1.9 years

First QC Date

March 2, 2026

Last Update Submit

April 29, 2026

Conditions

Keywords

ChineseQuality of LifePatientsSurvivors26-025

Outcome Measures

Primary Outcomes (2)

  • Proportion of eligible participants who enroll in the trial.

    2 years

  • Proportion of participants who complete treatment

    Pproportion of assessments that are completed, with completion defined as submitting the 24-week assessment with a minimum of the FACT-G completed.

    24 weeks

Study Arms (8)

1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings.

Other: Cancer EducationOther: Meaning-Centered CounselingOther: Peer SupportOther: Enhanced Standard Care

2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions.

Other: Cancer EducationOther: Meaning-Centered CounselingOther: Enhanced Standard Care

3 - Cancer Education + Peer Support + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings.

Other: Cancer EducationOther: Peer SupportOther: Enhanced Standard Care

4 - Cancer Education + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.

Other: Cancer EducationOther: Enhanced Standard Care

5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings

Other: Meaning-Centered CounselingOther: Peer SupportOther: Enhanced Standard Care

6 - Meaning-Centered Counseling- + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Counseling sessions, will have 3 weekly sessions.

Other: Meaning-Centered CounselingOther: Enhanced Standard Care

7 - Peer Support + Enhanced Standard Care

EXPERIMENTAL

All participants will also receive cancer information materials and resources. Peer support meetings, will have 3 monthly meetings

Other: Peer SupportOther: Enhanced Standard Care

8 - Enhanced Standard Care

ACTIVE COMPARATOR

All participants will also receive cancer information materials and resources.

Other: Enhanced Standard Care

Interventions

Cancer Education on side effects and their management, treatment options, advance care planning, and survivorship. Each session will last about 30-60 minutes and will be completed over the phone or by video call.

1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care3 - Cancer Education + Peer Support + Enhanced Standard Care4 - Cancer Education + Enhanced Standard Care

Peer support aims to increase social support for CCS to decrease cancer stigma, which has been associated with greater psychological distress, especially among less acculturated Chinese immigrant CCS. The meetings will include up to 6-8 Mandarin-speaking patients and survivors and will last about 90 minutes.

1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care3 - Cancer Education + Peer Support + Enhanced Standard Care5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care7 - Peer Support + Enhanced Standard Care

enhanced standard care ( written cancer information materials in Chinese and referral to counseling)

1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care3 - Cancer Education + Peer Support + Enhanced Standard Care4 - Cancer Education + Enhanced Standard Care5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care6 - Meaning-Centered Counseling- + Enhanced Standard Care7 - Peer Support + Enhanced Standard Care8 - Enhanced Standard Care

Meaning-centered counseling aims to activate culturally relevant meaning-focused coping strategies in Chinese-speaking patients and survivors (CCS). Each session will last about 45-60 minutes and will be completed over the phone or by video call.

1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care6 - Meaning-Centered Counseling- + Enhanced Standard Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with cancer (any type/stage) (per EMR for MSK patients or self-report for external participants) within the last 5 years
  • Age ≥ 18 years (per EMR for MSK patients or self-report for external participants)
  • Self-Report Criteria:
  • Of Chinese descent
  • Speaks Mandarin "well" or "very well"
  • Moderately low HRQOL (\<70 FACT-G score)4, 48
  • Resides in New York or New Jersey
  • Agrees to participate via telehealth (video or phone)
  • Agrees to be audio-recorded

You may not qualify if:

  • Self-Report Criteria:
  • Per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol is able to provide. If a participant receives a score of \> 0 on item 9 of the PHQ-9,5 they will be referred to study PI for further evaluation using the Columbia-Suicide Severity Rating Scale. They will be excluded from participation in this study if there is presence of suicidal risk, determined by affirmative response(s) on the Columbia-Suicide Severity Rating Scale (C-SSRS)
  • Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
  • Cognitive impairment (Montreal Cognitive Assessment 5 Minute - telephone version with a score \< 12)
  • Per consenting professional determination, unable to understand the informed consent procedure
  • Participation in study #14-076: Adaptation of Individual Meaning-Centered Psychotherapy for Chinese immigrant cancer patients)
  • Currently receiving/have received psychotherapy/counseling/peer support within the last 6 months (patients being treated solely with psychotropic medications will not be excluded if they are not receiving psychotherapy/counseling/peer support)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, 07920, United States

RECRUITING

Memorial Sloan Kettering Monmouth (All Protocol Activities)

Middletown, New Jersey, 07748, United States

RECRUITING

Memorial Sloan Kettering Bergen (All Protocol Activities)

Montvale, New Jersey, 07645, United States

RECRUITING

Memorial Sloan Kettering Cancer Center Suffolk- Commack (All Protocol Activities)

Commack, New York, 11725, United States

RECRUITING

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, 10604, United States

RECRUITING

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, 10065, United States

RECRUITING

Memorial Sloan Kettering Nassau (All Protocol Activities)

Uniondale, New York, 11553, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Florence Lui, PhD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Florence Lui, PhD

CONTACT

Jennifer Leng, MD, MPH

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
FACTORIAL
Model Details: Using a 2x2x2 factorial design. Participants will be randomized to receive a combination of one or more culturally tailored telehealth-delivered intervention components.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 2, 2026

First Posted

March 6, 2026

Study Start

February 27, 2026

Primary Completion (Estimated)

February 1, 2028

Study Completion (Estimated)

February 1, 2028

Last Updated

May 1, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Locations