Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.

NCT07453732 | Not Yet Recruiting

• 1 other identifier: 25-2297
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients

Conditions

Partial-thickness Burn; Pain; Second Degree Burn

Outcome Measures

Primary Outcomes (1)

• Pain scores, as measured using Number Pain Rating Scale

  The Numeric Pain Rating Scale is a unidimensional subjective measure of pain intensity in adults, consisting of a scale from 0 to 10, where 0 represents "no pain" and 10 represents "worst pain imaginable" (or "worst possible pain").

  Before, during and after each wound care session during hospitalization, approximately 14 days

Secondary Outcomes (5)

• Total use of opioids and benzodiazepines during wound care sessions

  During hospitalization, approximately 14 days

• Time to wound closure

  During hospitalization or at follow-up in clinic, approximately within 1 month

• Skin graft rate

  During hospitalization, approximately 14 days

• Burn wound infection rate

  During hospitalization, approximately 14 days

• Number of participants with at least one adverse event

  End of study (1 year)

Other Outcomes (3)

• Patient recruitment rate

  End of study (1 year)

• Adherence to study intervention

  End of study (1 year)

• Adherence to pain score documentation

  End of study (1 year)

Study Arms (1)

Banana leaf dressing

EXPERIMENTAL

Participants will be treated with banana leaf as a primary non-adherent dressing on their burn wounds

Device: Banana leaf dressing

Interventions

Banana leaf dressing DEVICE

Sterilized banana leaf as a primary non-adherent burn dressing

Banana leaf dressing

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \<10% Total body surface area (TBSA) partial thickness burns
• Patients age 18 to 99
• Primary admission (inpatient) to the UCHealth Burn and Frostbite Center
• Burns \<48 hours old on admission

You may not qualify if:

• Patients \<18 years
• Patients who are pregnant, incarcerated, or cognitively impaired
• Burns \>48 hours old on admission
• Patients with concurrent traumatic injuries
• Patients with chemical, electrical, or friction burns
• Full thickness burns
• Burns to sensitive areas: face, genitals, hands, feet
• Burns with evidence of infection on admission
• Patients with a known allergy to bananas or latex
• Patients with opioid use disorder or methamphetamine use disorder

Sponsors & Collaborators

• University of Colorado, Denver: lead

Study Sites (1)

University of Colorado Hospital

Aurora, Colorado, 80045, United States

Location

Related Publications (7)

• Chendake S, Kale T, Manavadaria Y, Motimath AS. Evaluation of Banana Leaves (Musa paradisiaca) as an Alternative Wound Dressing Material Compared to Conventional Petroleum Jelly Gauze Dressing in Contused, Lacerated and Sutured Wounds Over the Head, Neck and Face Region. Cureus. 2021 Oct 6;13(10):e18552. doi: 10.7759/cureus.18552. eCollection 2021 Oct.

  PMID: 34765339 BACKGROUND

• Guenova E, Hoetzenecker W, Kisuze G, Teske A, Heeg P, Voykov B, Hoetzenecker K, Schippert W, Moehrle M. Banana leaves as an alternative wound dressing. Dermatol Surg. 2013 Feb;39(2):290-7. doi: 10.1111/dsu.12067. Epub 2012 Dec 10.

  PMID: 23387359 BACKGROUND

• Srinivas CR, Sundaram VS, Raju BA, Prabhu SK, Thirumurthy M, Bhaskar AC. Achieving asepsis of banana leaves for the management of toxic epidermal necrolysis. Indian J Dermatol Venereol Leprol. 2006 May-Jun;72(3):201-2. doi: 10.4103/0378-6323.25779.

  PMID: 16766833 BACKGROUND

• Gore MA, Akolekar D. Evaluation of banana leaf dressing for partial thickness burn wounds. Burns. 2003 Aug;29(5):487-92. doi: 10.1016/s0305-4179(03)00050-0.

  PMID: 12880731 BACKGROUND

• Gore MA, Akolekar D. Banana leaf dressing for skin graft donor areas. Burns. 2003 Aug;29(5):483-6. doi: 10.1016/s0305-4179(03)00049-4.

  PMID: 12880730 BACKGROUND

• Dharnidharka VR, Kandoth PW. Use of banana leaves in Stevens-Johnson syndrome. Pediatr Dermatol. 1994 Sep;11(3):280-1. doi: 10.1111/j.1525-1470.1994.tb00606.x. No abstract available.

  PMID: 7971569 BACKGROUND

• Hop MJ, Polinder S, van der Vlies CH, Middelkoop E, van Baar ME. Costs of burn care: a systematic review. Wound Repair Regen. 2014 Jul-Aug;22(4):436-50. doi: 10.1111/wrr.12189.

  PMID: 25041616 BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Cameron Gibson, MD

  University of Colorado, Denver

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Cameron Gibson, MD

CONTACT

720-848-3251; cameron.2.gibson@cuanschutz.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2026
• First Posted: March 6, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): April 30, 2027
• Study Completion (Estimated): April 30, 2027
• Last Updated: March 24, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)