Association Between Extremity Muscle Strength and Functional Outcomes in Children With Cerebral Palsy

NCT07448207 | Completed

• 1 other identifier: HU-FTR-AS-01
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate whether upper and lower extremity muscle strength is a factor in activity, participation and quality of life parameters in school-age children with CP and to reveal the difference in upper and lower extremity muscle strength compared to typically developing peers.

Conditions

Cerebral Palsy (CP)

Keywords

Muscle Strength; Participation; Quality of Life; Cerebral Palsy

Outcome Measures

Primary Outcomes (1)

• Upper and Lower Extremity Isometric Muscle Strength Measured by Hand-Held Dynamometer (ActivForce 2, Activbody, San Diego, CA, USA).

  Isometric muscle strength of the following muscle groups was assessed using the "Make Test" with a portable hand-held dynamometer (ActivForce 2; Activbody, San Diego, CA, USA): Shoulder abductors, Shoulder extensors, Elbow flexors, Elbow extensors, Hip abductors, Hip extensors, Knee flexors, Knee extensors. Muscle strength values were recorded in kilograms (kg). Higher values indicate greater muscle strength.

  1 day (single assessment session)

Secondary Outcomes (4)

• Pediatric Evaluation of Disability Inventory - Computer Adaptive Test (PEDI-CAT) Domain Scores

  1 day

• Cerebral Palsy Quality of Life Questionnaire (CP QOL) Total Score

  1 day

• Assessment of Life Habits (LIFE-H) Total Score

  1 day

• Pediatric Outcomes Data Collection Instrument (PODCI) Global Function Score

  1 day

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children with cerebral palsy who applied to the Paediatric Physiotherapy and Cerebral Palsy Unit of the Department of Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, and children of the same age group with typical development were included in the study.

You may qualify if:

• Having been diagnosed with cerebral palsy,
• Being classified as Level I-II-III on the Gross Motor Classification System,
• Being classified as Level I-II on the Communication Function Classification System (IFSS) for Individuals with Cerebral Palsy,
• Having turned 6 years old by the start of the study and not having turned 12 years old by the end of the study.
• Not having been diagnosed with any neurological disorder,
• Having turned 6 years old by the start of the study and not having turned 12 years old by the end of the study.

You may not qualify if:

• Have a Gross Motor Classification System Level IV-V,
• Have a Communication Function Classification System (IFSS) Level III, IV, and V for individuals with cerebral palsy,
• Having undergone Botulinum Toxin-A (BTX-A) injection in the last 6 months,
• Having undergone orthopaedic surgery in the last 6 months,
• Using medication that may affect muscle strength,
• Having cardiovascular problems.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University, Faculty of Physical Therapy and Rehabilitation

Ankara, İzmir, 35410, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Mintaze Kerem Günel, PT, Prof. Dr.

  Hacettepe University, Faculty of Physical Therapy and Rehabilitation

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 26, 2026
• First Posted: March 4, 2026
• Study Start: September 1, 2022
• Primary Completion: June 1, 2023
• Study Completion: June 15, 2023
• Last Updated: March 4, 2026

Record last verified: 2026-03

Locations

TU (1)