NCT07447921

Brief Summary

The goal of this clinical trial is to learn whether improving caregivers' mental health and parenting practices can enhance child wellbeing among Congolese refugee families living in the Nyarugusu Refugee Camp, Tanzania. The WEMA trial ("Wellbeing through combined Evidence-based tools for Mental health and Attuned parenting") is a three-arm, family-level cluster-randomized, controlled superiority trial involving 324 families (approximately 648 children aged 7-10 years and their two primary caregivers). Participants and intervention facilitators will know which program a family receives, but outcome assessors (enumerators) will not know group assignment. The main questions it aims to answer are:

  • Does Self-Help Plus (SH+), a World Health Organization (WHO) group stress-management program, improve children's emotional and behavioral functioning at 12 months post-intervention, compared with usual care?
  • Does adding Interaction Competencies with Children for Parents (ICC-P), a participatory parenting program, after SH+ further improve children's emotional and behavioral functioning at 12 months post-intervention, compared with SH+ alone? Researchers will compare (1) Usual Care, (2) SH+, and (3) SH+ followed by ICC-P to see whether SH+ improves outcomes versus usual care, and whether SH+ followed by ICC-P provides additional benefits beyond SH+ alone. Participants will:
  • Be assigned by chance by family clusters to one of three groups: Usual Care, SH+, or SH+ followed by ICC-P.
  • Receive either (a) information about available psychosocial and mental health services (Usual Care), (b) SH+ (five group sessions delivered by trained non-specialists), or (c) SH+ followed by ICC-P (a four-day participatory parenting training to strengthen positive parenting and reduce harsh discipline).
  • Complete study assessments at baseline, 3 months, and 12 months post-intervention. The primary outcome is children's emotional and behavioral functioning, measured using the Pediatric Symptom Checklist-17 (PSC-17) at 12 months post-intervention. Secondary outcomes include children's wellbeing and quality of life, as well as caregivers' mental health, well-being, and parenting practices. Additional exploratory outcomes will also be assessed, including measures collected from caregivers and behavioral tasks with children. The trial is implemented by Uppsala University in collaboration with the Dar es Salaam University College of Education (DUCE) and partners, with funding from the Swedish Research Council (grant no. 2022-02476).

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,296

participants targeted

Target at P75+ for not_applicable

Timeline
11mo left

Started Mar 2026

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress30%
Mar 2026Jul 2027

First Submitted

Initial submission to the registry

February 25, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 4, 2026

Completed
11 days until next milestone

Study Start

First participant enrolled

March 15, 2026

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2027

Last Updated

March 4, 2026

Status Verified

February 1, 2026

Enrollment Period

1.3 years

First QC Date

February 25, 2026

Last Update Submit

February 25, 2026

Conditions

Keywords

Mental healthChild developmentParentingRefugeesSelf-Help PlusInteraction Competencies with Children - for ParentsTanzania

Outcome Measures

Primary Outcomes (1)

  • Caregiver-reported child emotional and behavioral functioning (Pediatric Symptom Checklist-17, PSC-17)

    Emotional and behavioral functioning of children aged 7-10 years will be assessed using the Pediatric Symptom Checklist-17 (PSC-17), a 17-item caregiver-report screening tool for psychosocial problems (total score range 0-34; higher scores indicate greater difficulties). Each child's PSC-17 will be completed independently by both primary caregivers. The primary outcome metric is the mean (average) of the two caregiver-reported PSC-17 total scores for each child at 12 months post-intervention. PSC-17 subscales (internalizing, externalizing, attention) will be examined in secondary/exploratory analyses.

    Baseline, 3 months post-intervention, and 12 months post-intervention

Secondary Outcomes (12)

  • Self-reported child emotional and behavioral functioning (Youth-adapted Pediatric Symptom Checklist-17, Y-PSC-17)

    Baseline and 12-months post-intervention

  • Child health-related quality of life (KINDL-R)

    Baseline, 3 months post-intervention, and 12 months post-intervention

  • Psychological distress (Kessler Psychological Distress Scale, K6)

    Baseline, 3 months post-intervention, and 12 months post-intervention

  • Depression (Patient Health Questionnaire-9, PHQ-9)

    Baseline, 3 months post-intervention, and 12 months post-intervention

  • Anxiety (Generalized Anxiety Disorder 7-item scale, GAD-7)

    Baseline, 3 months post-intervention, and 12 months post-intervention

  • +7 more secondary outcomes

Other Outcomes (8)

  • Emotion recognition task (facial and vocal expressions)

    Baseline and 12 months post-intervention

  • Executive functioning (Dimensional Change Card Sort, DCCS)

    Baseline and 12 months post-intervention

  • Theory of mind (false-belief tasks)

    Baseline and 12 months post-intervention

  • +5 more other outcomes

Study Arms (3)

Self Help plus

EXPERIMENTAL

Families assigned to this arm receive the World Health Organization's Self-Help Plus (SH+), a brief, group-based stress-management program for caregivers. The two primary caregivers in each family participate. SH+ is delivered by trained non-specialist facilitators using a standardized, audio-guided format with an illustrated self-help manual and structured group discussion. The program consists of five sessions (about two hours each), with at least three days between sessions.

Behavioral: Self Help Plus

Self-Help Plus + Interaction Competencies with Children - for Parents (SH+ + ICC-P)

EXPERIMENTAL

Families assigned to this arm receive SH+ first, followed by Interaction Competencies with Children for Parents (ICC-P). The two primary caregivers in each family participate. SH+ is delivered as described above (five group sessions, approximately two hours each, spaced at least three days apart, delivered by trained non-specialists using standardized audio-guided materials and an illustrated manual). After SH+ is completed, caregivers receive ICC-P, a participatory parenting program designed to strengthen positive, responsive caregiving and reduce harsh or violent discipline. ICC-P is delivered as three consecutive full training days plus one refresher training day six weeks later, following a manualized group format.

Behavioral: Self Help PlusBehavioral: Interaction Competencies with Children - for Parents

Usual Care (Control)

NO INTERVENTION

Participants in this arm receive Usual Care (UC). At baseline, caregivers are provided with a standardized information leaflet describing existing mental health and psychosocial support services available in the refugee camp, including organization names, contact information, and types of services offered. No structured intervention is delivered as part of this arm.

Interventions

Self Help PlusBEHAVIORAL

The Self-Help Plus (SH+) intervention is a stress management program developed by the World Health Organization (WHO). It is based on Acceptance and Commitment Therapy and designed for use in resource-limited and humanitarian settings. SH+ is delivered in five group sessions led by trained non-specialist facilitators using pre-recorded audio, structured manuals, and illustrated participant guides in Kiswahili. The program teaches practical skills for coping with stress and managing difficult thoughts and emotions. Each session lasts approximately two hours and includes individual reflection and guided group discussion.

Self Help plusSelf-Help Plus + Interaction Competencies with Children - for Parents (SH+ + ICC-P)

ICC-P is a four-day, group-based intervention designed to strengthen positive parenting and reduce harsh or violent discipline. It combines theoretical input with practical exercises, group discussions, and role-playing. A refresher session is held six weeks later to reinforce learning and promote sustainability. Both interventions are delivered by trained facilitators under supervision to ensure fidelity.

Self-Help Plus + Interaction Competencies with Children - for Parents (SH+ + ICC-P)

Eligibility Criteria

Age7 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Families residing in Nyarugusu Refugee Camp, Tanzania
  • Congolese refugee origin (for cultural and linguistic homogeneity)
  • Two primary caregivers (one male, one female) aged 18 years or older, caring for at least two children aged 7-10 years
  • Ability to speak and understand Kiswahili
  • Willingness to provide informed consent (and child assent)
  • No plans to leave the camp within the next 12 months

You may not qualify if:

  • Caregivers currently enrolled in other mental health or parenting programs
  • Caregivers displaying imminent suicide risk, psychosis, or severe cognitive impairment that would impede participation
  • Children with known developmental disabilities reported by caregivers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Dar es Salaam University College of Education

Dar es Salaam, Dar es Salaam Region, Tanzania

Location

Dar es Salaam University College of Education

Dar es Salaam, Dar es Salaam Region, Tanzania

Location

Related Publications (2)

  • Kabelege E, Kirika A, Nkuba M, Hermenau K, Schreiber A, Hoeffler A, Hecker T. Improving Parent-Child Interaction and Reducing Parental Violent Discipline - a Multi-Informant Multi-Method Pilot Feasibility Study of a School-Based Intervention. J Fam Violence. 2025;40:799-810. doi: 10.1007/s10896-023-00679-4.

    BACKGROUND
  • Tol WA, Leku MR, Lakin DP, Carswell K, Augustinavicius J, Adaku A, Au TM, Brown FL, Bryant RA, Garcia-Moreno C, Musci RJ, Ventevogel P, White RG, van Ommeren M. Guided self-help to reduce psychological distress in South Sudanese female refugees in Uganda: a cluster randomised trial. Lancet Glob Health. 2020 Feb;8(2):e254-e263. doi: 10.1016/S2214-109X(19)30504-2.

    PMID: 31981556BACKGROUND

MeSH Terms

Conditions

Psychological Well-Being

Condition Hierarchy (Ancestors)

Personal SatisfactionBehavior

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessors (enumerators) and data analysts will be blinded to group allocation. Enumerators conducting baseline, 3- and 12-month follow-up assessments will not be informed of participants' intervention assignment. Participants and facilitators cannot be blinded due to the nature of the psychosocial interventions (Self-Help Plus and Interaction Competencies with Children for Parents). Data analysts will work with datasets coded using neutral group labels, and unblinding will occur only after completion of the primary analyses.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 25, 2026

First Posted

March 4, 2026

Study Start

March 15, 2026

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

July 1, 2027

Last Updated

March 4, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Due to the sensitive nature of the data and the vulnerability of the study population, including refugee parents and children, individual participant data (IPD) will not be shared. Data privacy concerns and ethical constraints related to participant protection in a humanitarian setting prevent open sharing of de-identified datasets.

Locations