NCT07446985

Brief Summary

Women with polysyctic ovarian syndrome (PCOS) usually develop many complications including asthma. Nowdays, diet restriction combimed with phsyical exercises may improve both problems

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 7, 2026

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

February 26, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 3, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2026

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2026

Completed
Last Updated

March 3, 2026

Status Verified

February 1, 2026

Enrollment Period

5 months

First QC Date

February 26, 2026

Last Update Submit

February 26, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • forced vital capcity

    it is a pulmonary function testing

    it will be measured after 12 weeks

Secondary Outcomes (10)

  • forced expiratory volume

    It will be measured after 12 weeks

  • forced expiratory volume to forced expiratory capcity

    It will be measured after 12 weeks

  • body mass index

    It will be measured after 12 weeks

  • waist circumference

    it will be measured after 12 weeks

  • waist hip ratio

    It will be measured after 12 weeks

  • +5 more secondary outcomes

Study Arms (2)

group number 1

EXPERIMENTAL

Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks.

Behavioral: exercise plus limiitng diet

group number 2

ACTIVE COMPARATOR

Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

Behavioral: limiting diet

Interventions

Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks.

group number 1
limiting dietBEHAVIORAL

Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

group number 2

Eligibility Criteria

Age20 Years - 30 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsbased on self-representation of gender identity.
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • PCOS women
  • women with asthma
  • obese women (calss I)

You may not qualify if:

  • cardiac problems
  • renal problems
  • liver problems

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Giza, Dokki, Egypt

RECRUITING

MeSH Terms

Conditions

Polycystic Ovary SyndromeAsthma

Interventions

Exercise

Condition Hierarchy (Ancestors)

Ovarian CystsCystsNeoplasmsOvarian DiseasesAdnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital DiseasesGonadal DisordersEndocrine System DiseasesBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ali MA Ismail, lecturer

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ali MA Ismail, lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

Study Record Dates

First Submitted

February 26, 2026

First Posted

March 3, 2026

Study Start

February 7, 2026

Primary Completion

June 30, 2026

Study Completion

July 15, 2026

Last Updated

March 3, 2026

Record last verified: 2026-02

Locations