Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation

NCT07445672 | Not Yet Recruiting DMC

• 1 other identifier: soh-med-25-9----2PD
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

we use two different technique of anaesthesia for anaesthesia of patient undergoining CPC operation (20 each) were comparable with regard to demographic data and hemodynamic variables, IOP. After approval by our local Ethics Committee and written informed consent, 40 ASA physical status I, II or III patients scheduled for elective CBC operations were included in this study group s anasthetized with sevofluran while group p anaesthetized with propofol with repeated measurment of intraocular pressure of the other eye to detect which method better for IOP.

Conditions

Patient Cataract

Keywords

anaesthesia effect on IOP

Outcome Measures

Primary Outcomes (1)

• measurement of Intra ocular pressure during different type of anesthesia

  2 minute after administration of muscle relaxant and every 5 minute until termination of surgery

Study Arms (2)

group P patient anaesthetized by propofol

ACTIVE COMPARATOR

glaucoma patient anaesthetized by propofol in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation

Drug: Propofol and Fentanyl administration

Grpoup S patient anesthetized by sevoflurane

ACTIVE COMPARATOR

glaucoma patient anaesthetized by Sevoflurane in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation

Drug: Sevoflurane and fentanyl administration

Interventions

Propofol and Fentanyl administration DRUG

Group P patient anaesthetized by propofol and fentanyle for induction and maintenance

group P patient anaesthetized by propofol

Sevoflurane and fentanyl administration DRUG

Group S patient anaesthetized by sevoflurane and fentanyl for induction and maintenance

Grpoup S patient anesthetized by sevoflurane

Eligibility Criteria

• Age: 15 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• ASA I to III

You may not qualify if:

• known allergies; adverse reactions to any of the anesthetic agents used in the study
• unstable angina or manifest congestive heart failure.
• airway management was expected to be difficult

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Suhag faculty of medicine

Sohag, Sohag Governorate, Egypt

Location

MeSH Terms

Interventions

Propofol; Sevoflurane

Intervention Hierarchy (Ancestors)

Phenols; Benzene Derivatives; Hydrocarbons, Aromatic; Hydrocarbons, Cyclic; Hydrocarbons; Organic Chemicals; Methyl Ethers; Ethers; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated

Central Study Contacts

waleed adel Ahmed, lecturer

CONTACT

00201006392210; waleidadel8514@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of anaesthesia and intensive care

Study Record Dates

• First Submitted: February 25, 2026
• First Posted: March 3, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): June 10, 2026
• Study Completion (Estimated): July 20, 2026
• Last Updated: March 27, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)