Integrated Chinese and Western Therapy for Cancer-Related Fatigue

NCT07445243 | Completed

• 1 other identifier: REC110-58
• Study Type: interventional
• Target: 86
• Locations: 1 country
• Sites: 1

Brief Summary

Cancer-related fatigue (CRF) is a common and debilitating symptom in patients with cancer. Evidence-based non-pharmacological approaches include sleep hygiene, physical activity, nutritional management, and traditional Chinese medicine (TCM). This study evaluates the clinical effectiveness of an interdisciplinary holistic program integrating Chinese and Western therapies for CRF among hospitalized cancer patients receiving integrated care. Approximately 100 participants will be enrolled and followed for up to 3 months.

Conditions

Cancer-related Fatigue; Neoplasms (Cancer / Tumors)

Keywords

Holistic care; Integrative medicine; Integrated Chinese and Western medicine; Traditional Chinese Medicine; Chinese herbal medicine; Sleep hygiene; Aromatherapy; Nutrition counseling; Oncology nursing; Cancer-related fatigue

Outcome Measures

Primary Outcomes (1)

• Change in Cancer-Related Fatigue (CRF) Score (0-10)

  CRF is assessed using the Taiwan Society of Cancer Palliative Medicine fatigue scale (0-10) during hospitalization. Peak CRF score is defined as the maximum recorded CRF score from admission to discharge. Discharge CRF score is defined as the last in-hospital CRF assessment prior to discharge. The primary outcome is the within-participant change in CRF score from peak to discharge.

  From admission (baseline) through discharge (last in-hospital assessment; up to 30 days)

Secondary Outcomes (2)

• Proportion of Participants With Moderate-to-Profound CRF at Discharge (CRF Score ≥4)

  At discharge (last in-hospital assessment; up to 30 days after admission)

• Distribution of CRF Severity Categories at Discharge (0, 1-3, 4-6, 7-8, 9-10)

  At discharge (last in-hospital assessment; up to 30 days after admission)

Study Arms (1)

Integrated Chinese and Western Holistic Care

EXPERIMENTAL

All participants receive an integrated Chinese and Western holistic care program during hospitalization for cancer-related fatigue management. The program includes routine fatigue assessment and individualized supportive care measures (education, sleep hygiene, exercise encouragement, aromatherapy and/or massage, nutrition consultation, and shared decision-making). Traditional Chinese Medicine consultation (e.g., acupuncture and/or Chinese herbal medicine) may be provided when clinically indicated.

Other: Integrated Chinese and Western Holistic Care Program

Interventions

Integrated Chinese and Western Holistic Care Program OTHER

An interdisciplinary integrative care program combining Western supportive care and Traditional Chinese Medicine to manage cancer-related fatigue in hospitalized oncology patients. Core components include fatigue assessment, patient education and symptom management guidance, sleep hygiene, exercise encouragement, aromatherapy and/or massage, nutrition assessment and counseling, and shared decision-making. Traditional Chinese Medicine consultation may provide acupuncture and/or Chinese herbal medicine according to patient needs and clinical judgment.

Integrated Chinese and Western Holistic Care

Eligibility Criteria

• Age: 20 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Signed informed consent form.
• Age 20 to 95 years.
• Receiving integrated Chinese and Western holistic care.
• Agree to provide clinically relevant data for this study.

You may not qualify if:

• Refuse to continue participation during the study period, or the family requests discontinuation (withdrawal).
• Psychiatric disorder that makes the participant unable to cooperate.

Sponsors & Collaborators

• Taichung Tzu Chi Hospital: lead

Study Sites (1)

Taichung Tzu Chi Hospital

Taichung, 42743, Taiwan

Location

MeSH Terms

Conditions

Neoplasms; Sleep Hygiene

Condition Hierarchy (Ancestors)

Health Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Attending Physician

Model Details: Single-group, nonrandomized, open-label, quasi-experimental evaluation of an interdisciplinary holistic care program for hospitalized adult patients with cancer-related fatigue. The program integrates nursing education, sleep hygiene (optional aromatherapy), exercise promotion, dietician consultation, and Traditional Chinese Medicine modalities.

Study Record Dates

• First Submitted: February 21, 2026
• First Posted: March 3, 2026
• Study Start: November 8, 2019
• Primary Completion: April 22, 2020
• Study Completion: April 22, 2020
• Last Updated: March 3, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)