NCT07438457

Brief Summary

The study was conducted to compare the effects of McKenzie Exercises with William exercises for pain, disability and quality of life in patients with sacroiliac joint pain

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

February 23, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 27, 2026

Completed
Last Updated

February 27, 2026

Status Verified

February 1, 2026

Enrollment Period

6 months

First QC Date

February 23, 2026

Last Update Submit

February 23, 2026

Conditions

Keywords

Core stabilityDisabilityMcKenzie exercisesMulligan mobilizationWilliam exercises

Outcome Measures

Primary Outcomes (3)

  • Numeric Pain Rating Scale (NPRS)

    NPRS is a simple tool which is used to assess intensity of pain. Patients have to rate their pain level on NPRS scale from 0 to 10. It provides a quick, quantifiable measure of pain, aiding healthcare providers in monitoring treatment efficacy and adjusting interventions accordingly.

    From enrollment to the end of treatment at 8 weeks.

  • Oswestry Disability Index (ODI)

    ODI is a widely known as questionnaire designed to measure the level of disability in patients with lower back pain. Comprising 10 sections, each focusing on daily activities such as pain intensity, personal care, lifting, walking, sitting, standing, sleeping, social life, traveling, and employment, the ODI assesses the impact of pain on functional abilities. Each section is scored from 0 to 5, with higher scores indicating greater disability. Summing the scores provides a percentage-based measure of disability, ranging from minimal to severe. The ODI is instrumental in clinical practice for evaluating treatment effectiveness and monitoring patient progress over time.

    From enrollment to the end of treatment at 8 weeks.

  • Short form-36 for Quality of Life (SF-36)

    SF-36 is a 36-question survey that looks at health-related quality of life in eight areas: physical functioning, role limitations due to physical and mental health, pain in the body, general health perceptions, vitality, social functioning, health. SF-36 is a common tool used in research and clinical settings to measure how diseases affect people, how treatments help people, and how well people are overall. It shows many different aspects of a patient's quality of life. Get a clear picture of both your physical and mental health by scoring each domain. This is useful for both initial tests and keeping an eye on changes in health over time.

    From enrollment to the end of treatment at 8 weeks.

Study Arms (2)

McKenzie Therapy

EXPERIMENTAL
Other: McKenzie ExercisesOther: Conventional Physical Therapy

William Exercises

ACTIVE COMPARATOR
Other: William ExercisesOther: Conventional Physical Therapy

Interventions

Prone on Elbows: The patient was lie on their stomach with their elbows positioned under the shoulders, allowing them to rest on their forearms. This position hold for 15 seconds, with the patient instructed to take deep breaths and relax. This exercise repeated 10 times to enhance spinal extension and relieve pressure. Prone Press-Ups: In this exercise, the patient was prone line and hands placed under shoulders. They gradually straighten their elbows, lifting the upper body within a pain-free range. Each press-up was held for 15 seconds and repeated 10 times, aiming to promote spinal extension and alleviate pain. Extension in Standing: The patient was stand in a balanced position and lean backward as far as possible, allowing their head to tip back, then return to a neutral stance. This extension was held for 15 seconds and repeated 10 times, with the goal of improving lumbar mobility and centralizing pain. Three sessions per week were continued for 8 weeks.

McKenzie Therapy

William exercises was performed to strengthen up the abdominal and gluteal musculature in an effort to manage the sacroiliac joint pain. In this pelvic tilt exercise, Single knee to Chest exercise, Double knee to Chest exercises and hamstring stretching was performed 3 sets of each exercise with hold for 8 to 10 sec and 10 repetitions each set was performed for three times a week. This was continued for 8 weeks.

William Exercises

Mulligan Mobilization: For Mulligan mobilization, the patient assumed a prone position. A posterior-to-anterior glide was applied to the sacroiliac joint in three sets of 10 repetitions. The patient was instructed to extend the leg simultaneously with the glide, helping to realign the joint and reduce discomfort by promoting proper joint movement. Hot Therapy: Heat therapy was administered to the lower back and sacroiliac joint (SIJ) area for 10 minutes to improve blood flow, reduce stiffness, and prepare tissues for further interventions. Transcutaneous Electrical Nerve Stimulation (TENS): TENS was applied as an analgesic modality. In the prone position, the patient underwent TENS therapy for 20 minutes at a frequency of 20-50 Hz. Two electrodes placed on the primary painful area, while the other two was be positioned along the path of the radiating nerve to help reduce pain and promote muscle relaxation.

McKenzie TherapyWilliam Exercises

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Both male and female age between 20 and 50 years
  • Patients with sacroiliac joint pain(PSIS) typically present to the buttocks
  • Pain on numeric pain rating scale ranges between 4-8
  • Three out of five tests are positive according to Leslett's criteria from following tests; "distraction test", "FABER Test", Compression Test, "Thigh Thrust test","Gaenslen's test"

You may not qualify if:

  • Patients with lumber stenosis and radiculopathy was excluded.
  • Patient diagnosed of spondylolisthesis and ankylosing spondylitis was not included in the study.
  • Pregnant and lactating females was excluded
  • Rheumatoid arthritis, hip fractures.
  • History of any prior orthopedic surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fatima Memorial Hospital

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (6)

  • Hides JA, Donelson R, Lee D, Prather H, Sahrmann SA, Hodges PW. Convergence and Divergence of Exercise-Based Approaches That Incorporate Motor Control for the Management of Low Back Pain. J Orthop Sports Phys Ther. 2019 Jun;49(6):437-452. doi: 10.2519/jospt.2019.8451. Epub 2019 May 15.

    PMID: 31092126BACKGROUND
  • Weerasekara I, Deam H, Bamborough N, Brown S, Donnelly J, Thorp N, Rivett DA. Effect of Mobilisation with Movement (MWM) on clinical outcomes in lateral ankle sprains: A systematic review and meta-analysis. Foot (Edinb). 2020 Jun;43:101657. doi: 10.1016/j.foot.2019.101657. Epub 2019 Nov 28.

    PMID: 32247262BACKGROUND
  • Kim J, Kim S, Shim J, Kim H, Moon S, Lee N, Lee M, Jin E, Choi E. Effects of McKenzie exercise, Kinesio taping, and myofascial release on the forward head posture. J Phys Ther Sci. 2018 Aug;30(8):1103-1107. doi: 10.1589/jpts.30.1103. Epub 2018 Aug 7.

    PMID: 30154609BACKGROUND
  • Alhakami AM, Davis S, Qasheesh M, Shaphe A, Chahal A. Effects of McKenzie and stabilization exercises in reducing pain intensity and functional disability in individuals with nonspecific chronic low back pain: a systematic review. J Phys Ther Sci. 2019 Jul;31(7):590-597. doi: 10.1589/jpts.31.590. Epub 2019 Jul 9.

    PMID: 31417227BACKGROUND
  • Hennemann V, Ziegelmann PK, Marcolino MAZ, Duncan BB. The McKenzie Method delivered by credentialed therapists for chronic low back pain with directional preference: systematic review with meta-analysis. J Man Manip Ther. 2025 Apr;33(2):96-111. doi: 10.1080/10669817.2024.2408084. Epub 2024 Oct 9.

    PMID: 39383118BACKGROUND
  • Yan H, Zhao P, Guo X, Zhou X. The effects of Core Stability Exercises and Mulligan's mobilization with movement techniques on sacroiliac joint dysfunction. Front Physiol. 2024 Apr 18;15:1337754. doi: 10.3389/fphys.2024.1337754. eCollection 2024.

    PMID: 38699145BACKGROUND

Study Officials

  • Humera Mubashar, MS-OMPT

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 23, 2026

First Posted

February 27, 2026

Study Start

June 1, 2025

Primary Completion

November 30, 2025

Study Completion

November 30, 2025

Last Updated

February 27, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations