NCT07438431

Brief Summary

Delayed-onset muscle soreness (DOMS) is characterized by pain, stiffness, and discomfort that typically develop 24-72 hours after unaccustomed or intense physical activity. Previous studies suggest that both Kinesio taping and the Graston technique may help reduce DOMS-related symptoms. However, these two approaches have not been directly compared, and their effects on muscle oxygen saturation, peak squat force, and lower-extremity response time remain unclear. Therefore, the aim of this study was to compare the short-term effects of Kinesio taping and the Graston technique in healthy participants with exercise-induced DOMS. A total of 36 participants were randomly allocated to three groups: a Kinesio taping group, a Graston technique group, and a control group that received no therapeutic intervention and recovered naturally. Pain severity, muscle oxygen saturation, peak squat force, and lower-extremity response time were assessed 0h after the DOMS-induction protocol, before the interventions, and again 48 hours after the DOMS-induction protocol, corresponding to 48 hours after the interventions were initiated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 20, 2024

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

February 18, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 27, 2026

Completed
Last Updated

August 13, 2026

Status Verified

August 1, 2026

Enrollment Period

12 months

First QC Date

February 18, 2026

Last Update Submit

August 11, 2026

Conditions

Keywords

physiotherapykinesio tapinggraston technique

Outcome Measures

Primary Outcomes (1)

  • Visual Analog Scale

    Pain severity was assessed using a 10-cm horizontal Visual Analog Scale (VAS), anchored by 0 ("no pain") and 10 ("worst imaginable pain"). Participants were asked to mark the point on the line that best represented their perceived pain intensity. The distance from the 0 anchor to the marked point was measured in centimetres using a ruler, with higher scores indicating greater pain severity. Pain was assessed separately at rest and during the squat task.

    48 hours

Secondary Outcomes (3)

  • Peak Squat Force

    48 hours

  • Response Time

    48 hours

  • Muscle Oxygen Saturation (SmO₂)

    48 hours

Study Arms (3)

Kinesio Taping

ACTIVE COMPARATOR

The group of individuals who will undergo kinesio taping application.

Other: kinesio taping

Graston Technique

EXPERIMENTAL

The group of individuals who will undergo Graston technique application.

Other: Graston Technique

Control

NO INTERVENTION

spontaneous recovery process

Interventions

In this study, a lymphatic Kinesio taping technique was applied over the quadriceps femoris muscle. Two 5-cm-wide Kinesio tapes were cut to an appropriate length according to the dimensions of the target area. Each tape was prepared in a fan-cut configuration consisting of an uncut base and five longitudinal tails. The base was applied proximally near the inguinal lymph nodes without tension. The five tails were then applied over the quadriceps femoris with approximately 15% tension, while the terminal portions of the tails were applied without tension. The application was performed with the participant in the supine position and the quadriceps muscle relaxed.

Kinesio Taping

The Graston technique, a form of instrument-assisted soft tissue mobilization, was applied using a stainless-steel instrument and baby oil as a lubricant. Participants were positioned supine with the quadriceps femoris relaxed. The convex surface of the instrument was applied sequentially over the vastus lateralis, rectus femoris, and vastus medialis muscles in a cranial-to-caudal direction. Each muscle was treated for 2 minutes, resulting in a total treatment duration of 6 minutes per session. The first session was performed immediately after the post-DOMS pre-intervention assessment, and the second session was performed 24 hours later.

Graston Technique

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Being between 18 and 30 years of age
  • Being classified as inactive according to the International Physical Activity Questionnaire
  • Having a body mass index below 25

You may not qualify if:

  • Presence of a chronic disease
  • History of lower extremity orthopedic disorders or surgery
  • Current lower extremity muscle pain
  • History of lower extremity trauma within the last month
  • Use of medications that may affect the musculoskeletal system (e.g., muscle relaxants, anti-inflammatory drugs)
  • Caffeine consumption within 24 hours before exercise
  • Participation in another exercise or intense physical activity within 24 hours before the test
  • Use of performance-enhancing supplements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi University

Ankara, Please Select, 06490, Turkey (Türkiye)

Location

Related Publications (4)

  • Heiss R, Lutter C, Freiwald J, Hoppe MW, Grim C, Poettgen K, Forst R, Bloch W, Huttel M, Hotfiel T. Advances in Delayed-Onset Muscle Soreness (DOMS) - Part II: Treatment and Prevention. Sportverletz Sportschaden. 2019 Mar;33(1):21-29. doi: 10.1055/a-0810-3516. Epub 2019 Mar 13.

  • Stanek J, Sullivan T, Davis S. Comparison of Compressive Myofascial Release and the Graston Technique for Improving Ankle-Dorsiflexion Range of Motion. J Athl Train. 2018 Feb;53(2):160-167. doi: 10.4085/1062-6050-386-16. Epub 2018 Jan 26.

  • Song W, Yang Y. Effect of Kinesio taping on delayed-onset muscle soreness in elite athletes. J Sports Med Phys Fitness. 2022 May;62(5):667-672. doi: 10.23736/S0022-4707.21.12280-7. Epub 2021 Mar 26.

  • Camacho MA, Herrera E, Barela JA, Delgado-Diaz DC. Kinesiotaping Diminishes Delayed Muscle Soreness but does not Improve Muscular Performance. Int J Sports Med. 2020 Aug;41(9):596-602. doi: 10.1055/a-1088-5223. Epub 2020 May 12.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Group allocation was concealed until completion of the DOMS-induction protocol and the post-DOMS pre-intervention assessment. Before allocation was revealed, neither the participants nor the physiotherapist supervising the DOMS-induction protocol were aware of the upcoming group assignment. After the baseline assessment, group allocation was disclosed for intervention delivery. The physiotherapist performing the outcome assessments remained blinded to group allocation throughout the study.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal İnvestigator

Study Record Dates

First Submitted

February 18, 2026

First Posted

February 27, 2026

Study Start

June 20, 2024

Primary Completion

June 1, 2025

Study Completion

June 1, 2025

Last Updated

August 13, 2026

Record last verified: 2026-08

Locations