Reproductive Prognosis in Women Seeking Offspring After Medical or Surgical Therapy for Endometriosis
SURGENDO
La Prognosi Riproduttiva Nelle Donne Che Ricercano Prole Dopo Terapia Medica o Chirurgica Per Endometriosi: Studio Multicentrico Italiano
1 other identifier
observational
650
1 country
1
Brief Summary
The study aims to compare the percentage of women with endometriosis who undergo PMA after medical vs surgical treatment and to describe conception patterns, pregnancy rates, and number of live vessels in women seeking offspring with endometriosis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2024
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2024
CompletedFirst Submitted
Initial submission to the registry
October 15, 2024
CompletedFirst Posted
Study publicly available on registry
February 27, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
ExpectedFebruary 27, 2026
February 1, 2026
1.5 years
October 15, 2024
February 24, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
endometriosis and PMA
Compare the number of women who undergo PMA after medical treatment with those who undergo PMA after surgery, then compare these data with those reported in the literature
2012 to 2021 diagnosis
Interventions
use of Medically assisted procreation techniques (PMA)
Eligibility Criteria
Women with endometriosis with an ultrasound or surgical diagnosis of endometriosis in one of the centres participating in the study who sought a pregnancy after diagnosis at an age of less than 40 years. The number of patients required will be approximately 650 in order to detect an absolute difference of ≥10% between the two groups ( medical or surgery terapy)..
You may qualify if:
- age \<40 years at the time of offspring research
- previous ultrasound or surgical diagnosis of endometriosis made in one of the endometriosis referral centres participating in the study
- search for offspring after diagnosis
- consent to the use of pseudonymised data for research purposes.
You may not qualify if:
- women without endometriosis
- age \>=40 years at the time of the search for offspring
- women who have undergone demolition surgery
- women who do not wish to have offspring
- women who have not given consent for their pseudonymised data to be used for research purposes
- severe male infertility factor (testicular sperm retrieval)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, MI, Italia, 20077, Italy
Related Publications (1)
Somigliana E, Daguati R, Vercellini P, Barbara G, Benaglia L, Crosignani PG. The use and effectiveness of in vitro fertilization in women with endometriosis: the surgeon's perspective. Fertil Steril. 2009 May;91(5):1775-9. doi: 10.1016/j.fertnstert.2008.02.004. Epub 2008 Apr 3.
PMID: 18394620RESULT
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Professor
Study Record Dates
First Submitted
October 15, 2024
First Posted
February 27, 2026
Study Start
October 1, 2024
Primary Completion
March 30, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
February 27, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will not share