Effect of Central Venous Catheter Dressing Types on Device-Related Pressure Injuries

NCT07437040 | Completed

• 1 other identifier: E-74555795-050.01.04-391967
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this clinical trial is to evaluate the effect of different central venous catheter dressing methods on the development of medical device-related pressure injuries in participants treated in the intensive care unit. This study aims to answer the following questions:

• What is the risk of pressure injury development in participants whose catheter dressings are performed using gauze and adhesive tape?
• What is the risk of pressure injury development in participants whose catheter dressings are performed using a chlorhexidine gluconate-containing transparent dressing?
• Is there a difference between these two dressing methods in terms of pressure injury development? The researchers will compare participants receiving gauze and adhesive tape dressings with participants receiving chlorhexidine gluconate-containing transparent dressings. Participants will:
• Receive catheter dressings according to the assigned dressing method based on randomization.
• Undergo regular catheter site assessments.
• Be evaluated for pressure injury development through skin assessments.
• Have their pressure injury risk monitored using the Braden Pressure Injury Risk Assessment Scale.

Conditions

Pressure Injuries; Medical Device Related Pressure Ulcer (MDRPU)

Keywords

Medical Device-Related Pressure Injury; Central Venous Catheter; Catheter Dressing; Pressure Injury; Intensive Care Unit; Braden Scale

Outcome Measures

Primary Outcomes (1)

• Medical device-related pressure injury at central venous catheter site.

  Incidence of Stage 1 medical device-related pressure injury at the central venous catheter insertion site, assessed according to the National Pressure Injury Advisory Panel (NPIAP) Staging System (Stage 1 represents non-blanchable erythema of intact skin; higher stages indicate greater tissue damage).

  Day 2, Day 9, and Day 16

Secondary Outcomes (2)

• Moisture at central venous catheter site

  Day 2, Day 9, and Day 16

• Pressure injury risk (Braden Scale)

  Day 1, Day 2, Day 9, and Day 16

Study Arms (2)

Gauze and Adhesive Tape

EXPERIMENTAL

Participants received central venous catheter dressing using gauze and adhesive tape according to institutional protocol.

Device: Gauze Dressing

Chlorhexidine Gluconate Transparent Dressing

EXPERIMENTAL

Participants received central venous catheter dressing using chlorhexidine gluconate-impregnated transparent dressing according to institutional protocol.

Device: Chlorhexidine Gluconate Transparent Dressing

Interventions

Gauze Dressing DEVICE

Central venous catheter dressing performed using sterile gauze and adhesive tape.

Gauze and Adhesive Tape

Chlorhexidine Gluconate Transparent Dressing DEVICE

Central venous catheter dressing performed using chlorhexidine gluconate-impregnated transparent dressing.

Chlorhexidine Gluconate Transparent Dressing

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Were aged 18 years or older,
• Underwent a new central venous catheter insertion,
• Had no pressure injury at the catheter insertion site at baseline,
• Provided informed consent (patient or legal representative).

You may not qualify if:

• Had a pressure injury at the catheter insertion site at baseline,
• Had dermatological conditions affecting skin integrity at the catheter site,
• Had a central venous catheter inserted at another institution,
• Were discharged or deceased before completion of follow-up.

Sponsors & Collaborators

• Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization: lead

Study Sites (1)

Prof. Dr. Cemil Taşçıoğlu City Hospital

Istanbul, Istanbul, 34384, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pressure Ulcer

Condition Hierarchy (Ancestors)

Skin Ulcer; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Hilal Uysal, PhD

  Bartın University, Department of Internal Medicine Nursing

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Nurse, Cardiovascular Surgery Unit

Model Details: This study is a randomized, parallel-group interventional trial. Eligible participants were assigned to one of two groups using randomization. In one group, central venous catheter dressings were performed using gauze and adhesive tape, while in the other group, chlorhexidine gluconate-impregnated transparent dressings were used. Participants remained in their assigned group throughout the study without crossover. Pressure injury development and risk assessments were evaluated and compared at predefined observation time points.

Study Record Dates

• First Submitted: February 22, 2026
• First Posted: February 27, 2026
• Study Start: August 10, 2022
• Primary Completion: December 10, 2022
• Study Completion: December 10, 2022
• Last Updated: February 27, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)