Outcomes of Double-face Augmentation Urethroplasty

NCT07436819 | Active Not Recruiting

• 1 other identifier: Urol1/2025
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 2

Brief Summary

Combined dorsal and ventral onlay augmentation for bul¬bar urethral reconstruction. Nontraumatic near-obliterative bulbar urethral strictures (BUS) of \<2 cm in length can be managed with non-transecting anastomotic bulbar urethroplasty or augmented anastomotic urethroplasty. However, if the obliterative stricture segment is \>2 cm and the urethral caliber is \<6F, augmentation with a single graft may not be sufficient. We present our initial experience with the double-face augmentation urethroplasty technique using buccal mucosal graft for near-obliterative bulbar urethral strictures through ventral or one-sided dorsal perineal approach and the analysis of the short-term outcomes of this technique.

Conditions

Urethral Stricture, Anterior; Urethral Stricture Disease

Keywords

double-face urethroplasty; buccal mucosal graft

Outcome Measures

Primary Outcomes (1)

• Urethral patency

  Urethral patency will be evaluated by Uroflowmetry, and Urethrography

  at least 2 years

Study Arms (1)

bulbar urethral stricture disease

EXPERIMENTAL

We present our initial experience with the double-face augmentation urethroplasty technique using buccal mucosal graft for near-obliterative bulbar urethral strictures through ventral or one-sided dorsal perineal approach and the analysis of the short-term outcomes of this technique.

Procedure: Double-face augmentation urethroplasty

Interventions

Double-face augmentation urethroplasty PROCEDURE

We present our initial experience with the double-face augmentation urethroplasty technique using buccal mucosal graft for near-obliterative bulbar urethral strictures through ventral or one-sided dorsal perineal approach and the analysis of the short-term outcomes of this technique.

bulbar urethral stricture disease

Eligibility Criteria

• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• The study will include patients with long segment bulbar urethral stricture (\>2 cm).Urethral lumen size less than 6 Fr.

You may not qualify if:

• Urethro-cutaneous fistula, urethral abscess or diverticulum. A scarred and unsalvageable urethral plate or scarred perineum. Lichen sclerosis (Balanitis xerotica obliterans). Unhealthy/unavailable buccal mucosa.

Sponsors & Collaborators

• Menoufia University: lead

Study Sites (2)

Menoufia faculty of medicine

Shibīn al Kawm, Al-Minoufiya, 52314, Egypt

Location

Menoufia faculty of medicine

Shibīn al Kawm, Al-Minufia, 52314, Egypt

Location

Related Publications (1)

• Ballesteros Ruiz C, Bandini M, Joshi PM, Bafna S, Sharma V, Yatam SL, Bhadranavar S, Patil A, Kulkarni SB. Dorsal approach for double-face bulbar urethroplasty: ventral inlay plus dorsal onlay using Kulkarni one-side dissection. Int Urol Nephrol. 2022 May;54(5):1039-1045. doi: 10.1007/s11255-022-03158-9. Epub 2022 Mar 6.

  PMID: 35249203 RESULT

Related Links

• Related Info

MeSH Terms

Conditions

Urethral Stricture

Condition Hierarchy (Ancestors)

Urethral Obstruction; Urethral Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: February 4, 2026
• First Posted: February 27, 2026
• Study Start: February 1, 2025
• Primary Completion (Estimated): August 10, 2026
• Study Completion (Estimated): February 1, 2027
• Last Updated: February 27, 2026

Record last verified: 2026-02

Locations

EG (2)