Long-Term Health Effects of Previous COVID-19 in Patients Undergoing Preoperative Anesthesia Evaluation

NCT07435805 | Recruiting

• 1 other identifier: EFSH-ANES-2025-19-23
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The COVID-19 pandemic has resulted in persistent health problems in a significant proportion of individuals after recovery from the acute infection. These long-term manifestations, commonly referred to as post-COVID condition or long COVID, may involve respiratory, cardiovascular, neurological, psychological, and general health domains. Understanding these sequelae is particularly important in patients undergoing preoperative anesthesia evaluation, as residual symptoms may influence perioperative risk assessment and clinical decision-making. This cross-sectional observational study aims to evaluate the long-term clinical and health effects of previous COVID-19 infection in adult patients presenting to the preoperative anesthesia clinic. Patients aged 18 years and older who report a history of confirmed COVID-19 infection will be included. Clinical data related to the acute infection period (disease severity, hospitalization, intensive care unit admission, oxygen therapy, and radiological findings) will be retrospectively obtained from hospital records. At the time of preoperative assessment, participants will complete a structured post-COVID clinical questionnaire to evaluate persistent symptoms across multiple organ systems. The study seeks to determine the prevalence and characteristics of long-term post-COVID symptoms and to explore potential associations between acute disease severity and ongoing health complaints. No additional medical intervention will be performed as part of this research.

Conditions

Post-COVID Condition; Long COVID; Sequelae of COVID-19

Keywords

Post-COVID Condition; COVID-19 Sequelae; Preoperative Assessment; Cross-Sectional Study

Outcome Measures

Primary Outcomes (1)

• Prevalence of Persistent Post-COVID Symptoms

  Assessment of respiratory, cardiovascular, neurological, psychological, and general health symptoms using a structured post-COVID clinical questionnaire administered during preoperative anesthesia evaluation.

  At the time of preoperative anesthesia assessment

Study Arms (1)

Previous COVID-19 Patients

Adult patients (≥18 years) presenting to the preoperative anesthesia clinic who report a history of laboratory-confirmed COVID-19 infection. Clinical data related to the acute infection period will be retrospectively obtained from hospital records, and persistent post-COVID symptoms will be assessed using a structured questionnaire at the time of preoperative evaluation.

Other: Post-COVID Clinical Assessment

Interventions

Post-COVID Clinical Assessment OTHER

Structured post-COVID symptom questionnaire and retrospective clinical data review performed at the time of preoperative anesthesia evaluation. No therapeutic intervention is applied.

Previous COVID-19 Patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18 years and older presenting to the preoperative anesthesia clinic of Elazığ Fethi Sekin City Hospital who report a previous laboratory-confirmed COVID-19 infection. The study population consists of surgical candidates undergoing routine preoperative evaluation. Clinical information regarding the acute COVID-19 period will be obtained retrospectively from hospital records, and persistent post-COVID symptoms will be assessed at the time of preoperative evaluation using a structured questionnaire.

You may qualify if:

• Age ≥18 years
• Presentation to the preoperative anesthesia clinic
• Self-reported history of laboratory-confirmed COVID-19 infection
• Ability to provide informed consent
• Willingness to complete the post-COVID clinical questionnaire

You may not qualify if:

• Age \<18 years
• No history of COVID-19 infection
• Refusal to participate or incomplete questionnaire
• Cognitive impairment or communication difficulties preventing reliable data collection

Sponsors & Collaborators

• Elazıg Fethi Sekin Sehir Hastanesi: lead

Study Sites (1)

Fethi Sekin City Hospital

Elâzığ, Elaziğ, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

OĞUZ KAĞAN BULUT, MD

CONTACT

+905327858130; oguzkaganbulut@hotmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 21, 2026
• First Posted: February 27, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 20, 2026
• Last Updated: February 27, 2026

Record last verified: 2026-02

Locations

TU (1)