Surgery for Obstructed Gastric Carcinoma

NCT07435025 | Active Not Recruiting

• 1 other identifier: 2105\17-Feb-2026
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to share in the trial. The main question is what is the better for management for obstructed gastric cancer; palliative resection or palliative bypass? We hypothesized that resection is better. patients will be divided into two groups. the primary outcome measure will be the relief of obstruction

Conditions

Gastric Cancer

Keywords

gastrectomy; palliative; bypass

Outcome Measures

Primary Outcomes (1)

• upper gastrointestinal symptoms

  upper gastrointestinal symptoms will be evaluated after surgery by Rhodes Index questionnaire. It is a validated, self-report instrument used to measure the intensity, frequency, and distress of upper gastrointestinal symptoms. The scale measures three main areas: nausea (frequency, duration, distress), vomiting (amount, frequency, distress), and retching (frequency, distress). It utilizes a 5-point Likert scale (0-4) to quantify the severity of these symptoms. 0 is the least amount of distress and 4 is the most distress.

  from one day to two weeks after surgery

Secondary Outcomes (4)

• anastmotic leak

  from day one to two weeks after surgery.

• ICU admission

  from day one to two weeks after surgery

• wound infection

  from day one to one month after surgery

• mortality

  from one day to one month after surgery

Study Arms (2)

Group I: obstructed gastric cancer patients

ACTIVE COMPARATOR

patients presented with emergency gastric obstruction

Procedure: palliative gastric resection

Group II: obstructed gastric cancer patients

ACTIVE COMPARATOR

patients presented with emergency gastric obstruction

Procedure: palliative bypass

Interventions

palliative gastric resection PROCEDURE

distal, subtotal or total gastrectomy with gastro-jejunostomy or eosphago-jejunostomy will be done

Group I: obstructed gastric cancer patients

palliative bypass PROCEDURE

palliative gastro-jejunostomy or eosphago-jejunostomy will be done

Group II: obstructed gastric cancer patients

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• emergency obstructed gastric cancer patients

You may not qualify if:

• non obstructed gastric cancer patients

Sponsors & Collaborators

• Zagazig University: lead

Study Sites (1)

faculty of medicine, Zagazig University

Zagazig, Sharqia Province, 44519, Egypt

Location

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases

Study Officials

• Reham Zakaria, M.D

  Zagazig University, Egypt

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of general surgery

Study Record Dates

• First Submitted: February 19, 2026
• First Posted: February 27, 2026
• Study Start: February 1, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: February 27, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share

Locations

EG (1)