Effect of Digitally Supported Medical Nutrition Therapy on Left Ventricular Ejection Fraction in Patients With ST-Elevation Myocardial Infarction

NCT07427199 | Recruiting

• 1 other identifier: 2025/012
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This study is designed to investigate the effect of a nutrition program supported by digital content on heart function in patients who have experienced a heart attack with ST-elevation. Participants will receive personalized dietary guidance and digital support materials for three months. The main goal is to determine whether this digital support materials can improve heart pumping function (measured by left ventricular ejection fraction). Participation involves following the dietary program and undergoing heart function measurements at the beginning, after one months and after three months.

Conditions

ST-elevation Myocardial Infarction (STEMI)

Outcome Measures

Primary Outcomes (1)

• Left Ventricular Ejection Fraction (LVEF)

  Left ventricular ejection fraction will be measured using echocardiography at baseline, 1 month, and 3 months to evaluate the effect of digital content-supported medical nutrition therapy.

  Baseline, 1 month, 3 months

Study Arms (2)

Standard Dietary Care / Control

NO INTERVENTION

Participants in this group receive standard dietary care as routinely provided to patients after ST-elevation myocardial infarction, without additional digital content support. Heart function (LVEF) will be measured at baseline, 1 month, and 3 months.

Digital Content-Supported Nutrition Therapy

EXPERIMENTAL

Participants in this group receive a personalized medical nutrition therapy program supported by digital content, including educational materials, meal planning guides, and remote support. The program lasts 3 months, with follow-up visits at baseline, 1 month, and 3 months. Heart function (LVEF) will be measured at each time point.

Behavioral: Digital Content-Supported Medical Nutrition Therapy

Interventions

Digital Content-Supported Medical Nutrition Therapy BEHAVIORAL

Participants receive a personalized medical nutrition therapy program supported by digital content. The program includes educational materials, meal planning guides, and remote support. The intervention lasts 3 months, with follow-up visits at baseline, 1 month, and 3 months. Heart function (LVEF) will be measured at each time point.

Digital Content-Supported Nutrition Therapy

Eligibility Criteria

• Age: 19 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals aged 19-65 who have fully completed the voluntary consent form
• Being of normal weight (BMI 18.5-24.9 kg/m²) or obese (30-34.99 kg/m²)
• Having suffered a heart attack with ST elevation (STEMI)
• To be enrolled in the study within the first 72 hours after hospital admission
• To be willing to participate in a follow-up period of at least 3 months

You may not qualify if:

• Those who did not sign the voluntary consent form
• Individuals aged over 65
• Weight loss exceeding 5% in the last 3 months
• Those with malignancy, chronic renal failure or severe systemic disease
• Patients unable to complete the questionnaires due to severe cognitive impairment
• Those who have previously received nutrition education or eating awareness training

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead
• Ondokuz Mayis University Training and Research Hospital: collaborator

Study Sites (1)

Ondokuz Mayıs Üniversitesi Tıp Fakültesi Hastanesi

Samsun, Atakum, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Infarction; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Central Study Contacts

Sena Yücel

CONTACT

+90 530 118 8468; senayucel633@gmail.com

Ziya Erokay Metin, Doç.Dr.

CONTACT

metinziya.erokay@sbu.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Echocardiography assessments are performed by a cardiologist blinded to group assignment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants are randomly assigned in a parallel design to either the intervention group receiving digital content-supported medical nutrition therapy or the control group receiving standard dietary care. Heart function (LVEF) will be measured at baseline, at 1 month, and at 3 months of follow-up.

Study Record Dates

• First Submitted: February 16, 2026
• First Posted: February 23, 2026
• Study Start: December 30, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: February 23, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)