NCT07425730

Brief Summary

To investigate biomarkers to identify pediatric SR-SLE patients by non-invasive echocardiographic techniques.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
1mo left

Started Feb 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress90%
Feb 2026Jul 2026

Study Start

First participant enrolled

February 1, 2026

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

February 6, 2026

Completed
17 days until next milestone

First Posted

Study publicly available on registry

February 23, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2026

Last Updated

April 28, 2026

Status Verified

February 1, 2026

Enrollment Period

5 months

First QC Date

February 6, 2026

Last Update Submit

April 22, 2026

Conditions

Systemic Lupus Erythematosus (SLE)

Keywords

lupusechocardiography

Outcome Measures

Primary Outcomes (1)

  • echocardiographic measurements

    echocardiographic measurements including chamber dimensions, LV systolic and diastolic function, valve disease, strain values and etc..

    6 months

Study Arms (1)

children with SLE

Pediatric patients fulfilled the American College of Rheumatology (ACR) criteria with disease onset at ages before 18 years。

Eligibility Criteria

Age7 Years - 17 Years
Sexall(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

pediatric lupus patients

You may qualify if:

  • fulfill the American College of Rheumatology (ACR) criteria
  • disease onset at ages before 18 years

You may not qualify if:

  • patients with a history of concomitant malignancy
  • patients with active bacterial, viral, fungal, mycobacterial infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Children's Medical Center

Shanghai, Shanghai Municipality, 200127, China

RECRUITING

MeSH Terms

Conditions

Lupus Erythematosus, Systemic

Condition Hierarchy (Ancestors)

Connective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Bao

    Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 6, 2026

First Posted

February 23, 2026

Study Start

February 1, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

July 1, 2026

Last Updated

April 28, 2026

Record last verified: 2026-02

Locations

CN(1)