Personalizing Mental Health Treatment for Youth and Families

NCT07425366 | Not Yet Recruiting

• 1 other identifier: 1R34MH140927
• Study Type: interventional
• Target: 64
• Locations: 0 countries
• Sites: N/A

Brief Summary

Incompatibility between evidence-based treatments (EBTs) and the cultural values, practices, and minoritized experiences of Latine youth and families contributes to racial-ethnic disparities in mental health treatment engagement and consequently mental health outcomes. The proposed study aims to develop and pilot a novel tool - the Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT) - for helping clinicians decide whether, when, and how to culturally adapt EBTs for individual Latine youth clients and thereby improve the cultural compatibility of EBTs for this underserved population. Completion of this study will result in a functional decision support tool designed to improve the quality and effectiveness of mental health services for Latine youths and promote mental health equity.

Conditions

Anxiety; Traumatic Stress; Disruptive Behavior; Depression

Keywords

child; anxiety; depression; traumatic stress; disruptive behavior; community mental health; National Institute of Mental Health; treatment adaptation; treatment fidelity; decision support tool

Outcome Measures

Primary Outcomes (1)

• DSM-5 Cross-Cutting Symptom Measure

  24-item self-report questionnaire that assesses symptoms across psychiatric diagnoses

  Baseline, and then quarterly until the end of treatment (approximately 1 year after baseline)

Secondary Outcomes (4)

• Revised Anxiety and Depression Scale

  Baseline, and then quarterly until the end of treatment (approximately 1 year after baseline)

• Strengths and Difficulties Questionnaire

  Baseline, and then quarterly until the end of treatment (approximately 1 year after baseline)

• UCLA PTSD Reaction Index

  Baseline, and then quarterly until the end of treatment (approximately 1 year after baseline)

• Columbia Impairment Scale

  Baseline, and then quarterly until the end of treatment (approximately 1 year after baseline)

Study Arms (2)

CFI + MATCH + CRAFTT

EXPERIMENTAL

Clinicians in this arm will assess for cultural factors that may influence treatment engagement or progress using the Cultural Formulation Interview (CFI), treat psychopathology using the Modular Approach to Treatment for Children (MATCH), and make cultural adaptation decisions using CRAFTT

Other: Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT); Diagnostic Test: Cultural Formulation Interview; Behavioral: Modular Approach to Therapy for Children

CFI + MATCH

ACTIVE COMPARATOR

Clinicians in this arm will assess for cultural factors that may influence treatment engagement or progress using the Cultural Formulation Interview (CFI), treat psychopathology using the Modular Approach to Treatment for Children (MATCH), and make cultural adaptation decisions using their best clinical judgement

Diagnostic Test: Cultural Formulation Interview; Behavioral: Modular Approach to Therapy for Children

Interventions

Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT) OTHER

CRAFTT will help clinicians assess whether their client is engaged and progressing, diagnose cultural risk and resilience factors, plan to implement cultural adaptations, implement cultural adaptations, and (re)evaluate client engagement and progress.

CFI + MATCH + CRAFTT

Cultural Formulation Interview DIAGNOSTIC_TEST

The Cultural Formulation Interview is a 16-item semi-structured interview that is organized into four sections: (i) definition of the problem; (ii) perceptions of cause, context, and support; (iii) factors affecting self-coping and past help seeking; and (iv) factors affecting current help seeking.

CFI + MATCH; CFI + MATCH + CRAFTT

Modular Approach to Therapy for Children BEHAVIORAL

The Modular Approach to Therapy for Children is a modular evidence-based treatment for youths, aged 5-15, with anxiety, depression, trauma, and disruptive behaviors.

CFI + MATCH; CFI + MATCH + CRAFTT

Eligibility Criteria

• Age: 5 Years - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Identify as Latino
• Fluent in English or Spanish
• years old
• Referred to individual psychotherapy with a participating clinician for a primary clinical concern involving anxiety, depression, trauma, or disruptive behaviors

Sponsors & Collaborators

• University of Oregon: lead

MeSH Terms

Conditions

Anxiety Disorders; Problem Behavior; Depression

Interventions

Dosage Forms

Condition Hierarchy (Ancestors)

Mental Disorders; Behavioral Symptoms; Behavior; Child Behavior

Intervention Hierarchy (Ancestors)

Pharmaceutical Preparations; Technology, Pharmaceutical; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 9, 2026
• First Posted: February 20, 2026
• Study Start (Estimated): January 1, 2027
• Primary Completion (Estimated): July 1, 2028
• Study Completion (Estimated): September 1, 2028
• Last Updated: February 20, 2026

Record last verified: 2026-02