Hidden Link Between Meatal Stenosis and Primary Nocturnal Enuresis in Children

NCT07424651 | Completed

• 1 other identifier: 2025130002
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to investigate the association between meatal stenosis and primary nocturnal enuresis severity, and evaluated therapeutic outcomes following surgical correction.

Conditions

Meatal Stenosis; Primary Nocturnal Enuresis; Children

Outcome Measures

Primary Outcomes (1)

• Association between Meatal Stenosis and primary nocturnal enuresis

  Association between Meatal Stenosis and primary nocturnal enuresis was assessed to determine whether there is a significant relationship between the presence of meatal stenosis and the occurrence of primary nocturnal enuresis in male children aged 7-12 years.

  3 years from collecting the data from the database

Secondary Outcomes (4)

• Resolution of primary nocturnal enuresis post-meatoplasty

  3 years from collecting the data from the database

• Need for Revision Meatoplasty

  3 years from collecting the data from the database

• Prevalence of Meatal Stenosis in primary nocturnal enuresis patients

  3 years from collecting the data from the database

• Incidence of complications

  3 years from collecting the data from the database

Study Arms (1)

Study group

Patients who underwent meatoplasty.

Procedure: Meatoplasty Primary nocturnal enuresis.

Interventions

Meatoplasty Primary nocturnal enuresis. PROCEDURE

Patients diagnosed with primary nocturnal enuresis.

Study group

Eligibility Criteria

• Age: 7 Years - 12 Years
• Gender Eligibility Details: Males diagnosed with primary nocturnal enuresis
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

This retrospective study population includes male children aged 7-12 years who presented with primary nocturnal enuresis at a pediatric urology clinic between October 2022 and December 2024.

You may qualify if:

• Male children aged 7-12 years.
• Diagnosed with primary nocturnal enuresis.
• Evaluated and treated at the study center between January 2021 and December 2024.
• Confirmed diagnosis of meatal stenosis based on clinical examination and uroflowmetry when indicated.
• Patients who underwent meatoplasty and completed the prescribed follow-up period.

You may not qualify if:

• Secondary enuresis (previously dry for ≥ 6 months before recurrence of bedwetting).
• Known neurological disorders (e.g., spina bifida, cerebral palsy) or developmental delays.
• Structural anomalies of the urinary tract other than meatal stenosis (e.g., posterior urethral valves, vesicoureteral reflux).
• Children who did not complete the follow-up or had incomplete clinical records.

Sponsors & Collaborators

• New Valley University: lead

Study Sites (1)

New Valley University

New Valley, Cairo Governorate, 72511, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Urology, Faculty of medicine, New Vally University, New Vally, Egypt

Study Record Dates

• First Submitted: February 14, 2026
• First Posted: February 20, 2026
• Study Start: January 31, 2021
• Primary Completion: March 10, 2025
• Study Completion: March 10, 2025
• Last Updated: February 20, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: The data will be available upon a reasonable request from the corresponding author.
• Access Criteria: After the end of study for one year.

Locations

EG (1)