NCT07424638

Brief Summary

This study aims to compare the frequency of occurrence of ipsilateral shoulder pain in patients undergoing thoracotomy with ultrasound-guided interscalene block, anterior suprascapular block as adjunct to epidural and epidural block only.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 20, 2026

Completed
1 day until next milestone

Study Start

First participant enrolled

February 21, 2026

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2026

Completed
Last Updated

February 24, 2026

Status Verified

February 1, 2026

Enrollment Period

5 months

First QC Date

February 14, 2026

Last Update Submit

February 21, 2026

Conditions

Interscalene BlockAnterior Suprascapular BlockThoracotomyShoulder Pain

Outcome Measures

Primary Outcomes (1)

  • Frequency of occurrence of ipsilateral shoulder pain

    Frequency of occurrence of ipsilateral shoulder pain will be recorded.

    72 hours postoperatively

Secondary Outcomes (10)

  • Degree of pain

    72 hours postoperatively

  • Mean arterial pressure

    48 hours postoperatively

  • Heart rate

    48 hours postoperatively

  • Incidence of complications

    72 hours postoperatively

  • Time to first request of rescue analgesia

    72 hours postoperatively

  • +5 more secondary outcomes

Study Arms (3)

Group (I)

EXPERIMENTAL

Patients will receive an ultrasound-guided interscalene block.

Other: Interscalene block

Group (S)

EXPERIMENTAL

Patients will receive an ultrasound-guided anterior suprascapular block.

Other: Anterior suprascapular block

Group (E)

ACTIVE COMPARATOR

Patients will not receive regional blocks apart from epidural analgesia.

Other: Epidural analgesia

Interventions

Interscalene blockOTHER

Patients will receive an ultrasound-guided interscalene block.

Group (I)
Anterior suprascapular blockOTHER

Patients will receive an ultrasound-guided anterior suprascapular block.

Group (S)
Epidural analgesiaOTHER

Patients will not receive regional blocks apart from epidural analgesia.

Group (E)

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \> 18 years and ≤ 65 years old.
  • American Society of Anesthesiologists (ASA) physical status II-III.
  • Body mass index 18-35 kg/m2.
  • Patients who have a confirmed diagnosis of lung cancer and are scheduled for elective open-lung surgery.

You may not qualify if:

  • Allergy to local anesthetics.
  • Known psychiatric or neurologic disorders.
  • Alcohol or narcotics abuse.
  • Contraindications to thoracic epidural or suprascapular block, or interscalene block, e.g., coagulopathy or local infection.
  • Pre-existing shoulder symptoms.
  • History of previous thoracotomy.
  • Severe restrictive or obstructive pulmonary disease.
  • Pre-existing contralateral diaphragmatic paralysis.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

RECRUITING

MeSH Terms

Conditions

Shoulder Pain

Interventions

Analgesia, Epidural

Condition Hierarchy (Ancestors)

ArthralgiaJoint DiseasesMusculoskeletal DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

AnalgesiaAnesthesia and Analgesia

Central Study Contacts

Mai M Elrawas, MD

CONTACT

00201222177242mai.elrawas@nci.cu.edu.eg

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of Anaesthesia, Intensive Care and Pain Management, National Cancer Institute, Cairo University Cairo University, Cairo, Egypt.

Study Record Dates

First Submitted

February 14, 2026

First Posted

February 20, 2026

Study Start

February 21, 2026

Primary Completion

July 30, 2026

Study Completion

July 30, 2026

Last Updated

February 24, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

The data will be available upon a reasonable request from the corresponding author after the end of study for one year.

Shared Documents
STUDY PROTOCOL
Time Frame
After the end of study for one year.
Access Criteria
The data will be available upon a reasonable request from the corresponding author.

Locations

EG(1)