NCT07424105

Brief Summary

The purpose of this study is to investigate the efficacy of optokinetic stimulation in stroke patients by examining its effects on spatial neglect, static balance, dynamic balance, and weight-bearing symmetry.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 20, 2026

Completed
Same day until next milestone

Study Start

First participant enrolled

February 20, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2026

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2026

Completed
Last Updated

February 20, 2026

Status Verified

February 1, 2026

Enrollment Period

2 months

First QC Date

February 14, 2026

Last Update Submit

February 14, 2026

Conditions

Stroke

Outcome Measures

Primary Outcomes (2)

  • Albert test

    It is the test used for screening of unilateral spatial neglect .the examiner asked to cross all the lines. The more un crossed lines the worst degree of spatial neglect.

    10 weeks

  • Catherine bergego scale (CGS)

    It is a 4 point scale used to indicate the severity of neglect .the total score out of 30 . the higher scores indicate the more severe the spatial neglect

    10 weeks

Secondary Outcomes (3)

  • Limit of stability (LOS)

    10 weeks

  • The Modified clinical test of sensory interaction on balance (m CTSIB)

    10 weeks

  • Center of pressure

    10 weeks

Study Arms (2)

Optokinetic stimulation + Traditional therapy

EXPERIMENTAL

Patients in this group will receive optokinetic stimulation and traditional therapy, twice weekly over a period of 10 weeks.

Other: Optokinetic stimulationOther: Traditional therapy

Sham optokinetic stimulation + Traditional therapy

SHAM COMPARATOR

Patients in this group will receive sham optokinetic stimulation and traditional therapy, twice weekly over a period of 10 weeks.

Other: Sham optokinetic stimulationOther: Traditional therapy

Interventions

Optokinetic stimulationOTHER

Patients will receive optokinetic stimulation (OKS) as an intervention for spatial neglect, based on observing moving visual stimuli to promote visual scanning of the neglected hemispace. With the patient properly positioned, the physiotherapist will apply virtual reality glasses supported by a mobile device displaying pre-prepared OKS videos. The videos will show vertical bars moving leftward at a fixed speed of 1 cm/s, with random color changes to maintain attention. Patients will be instructed to report each color change. OKS will be delivered in five 4-minute bouts separated by 1-minute rest intervals, totaling 20 minutes per session.

Optokinetic stimulation + Traditional therapy
Sham optokinetic stimulationOTHER

A static image consisting of black-and-white vertical bars will be projected for patients in this group. The bars will undergo random color changes similar to those used in the intervention group; however, no movement will be present.

Sham optokinetic stimulation + Traditional therapy
Traditional therapyOTHER

All participants in both groups will receive a selected physical therapy program for 30 min per session to enhance balance for 10 weeks.

Optokinetic stimulation + Traditional therapySham optokinetic stimulation + Traditional therapy

Eligibility Criteria

Age50 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient's age ranges from 50 to 65 years referred by neurologist.
  • Patient's will be diagnosed as stroke in the subacute stage
  • Patients will suffer from spatial neglect resulting from the stroke that screened by albert's test.
  • Patients are medically stable and able to understand and follow instructions.

You may not qualify if:

  • There is any previous neurological disability
  • There is general unstable conditions, history of epilepsy, cardiac pacemakers
  • There is sever cognitive disorder
  • There is visual field deficit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nahda University

Banī Suwayf, Egypt

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Abeer Abdelmoghney Mohamed, M.Sc

CONTACT

+20 10 20139616berrotheprof9@gmail.com

Nagwa Ibrahim Rehab, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 14, 2026

First Posted

February 20, 2026

Study Start

February 20, 2026

Primary Completion

May 5, 2026

Study Completion

May 15, 2026

Last Updated

February 20, 2026

Record last verified: 2026-02

Locations

EG(1)