NCT07423832

Brief Summary

Here is a plain-language, registry-appropriate Brief Summary you can paste into the form. It is written for patients, families, and healthcare providers: Brief Summary This study examines whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can reduce the severity of symptoms in adults experiencing post-traumatic stress disorder (PTSD) in Jordan. PTSD can develop after exposure to distressing or traumatic life events and may cause symptoms such as intrusive memories, avoidance, sleep problems, anxiety, and emotional distress. A total of 70 adult participants with moderate to severe PTSD symptoms were enrolled. Participants were assigned to one of two groups: an EMDR therapy group or a waitlist control group. Individuals in the EMDR group received structured therapy sessions delivered by a trained mental-health professional, while those in the waitlist group did not receive therapy during the study period but were offered treatment after the study ended. PTSD symptom severity was measured before treatment, immediately after the therapy sessions, and again one month later. The goal of the study was to determine whether EMDR therapy leads to meaningful and lasting reductions in PTSD symptoms compared with no immediate treatment. The findings of this research are intended to help healthcare providers and policymakers understand the value of EMDR as a non-pharmacological, evidence-based treatment option for individuals experiencing trauma-related distress, and to support improvements in mental-health services and trauma-informed care in Jordan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 15, 2023

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 25, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 14, 2024

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

February 14, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 20, 2026

Completed
Last Updated

February 20, 2026

Status Verified

February 1, 2026

Enrollment Period

10 months

First QC Date

February 14, 2026

Last Update Submit

February 14, 2026

Conditions

Keywords

PTSDEMDRSEVERITY OF SYMPTOMSJORDAN

Outcome Measures

Primary Outcomes (1)

  • Severity of post-traumatic stress symptoms

    Severity of post-traumatic stress symptoms measured using the Primary Care Post-Traumatic Stress Disorder Screen (PC-PTSD) questionnaire at baseline (T0), immediately post-intervention (T1), and one-month follow-up (T2).

    Baseline, immediately after intervention, and 1-month follow-up.

Study Arms (2)

EMDR Therapy Intervention

EXPERIMENTAL

Participants in this arm received Eye Movement Desensitization and Reprocessing (EMDR) therapy delivered by a licensed psychiatric mental-health professional trained in the standardized EMDR protocol. The intervention consisted of structured individual sessions (approximately 90 minutes each) conducted over several weeks. Sessions followed the established EMDR phases, including history taking, preparation, desensitization with bilateral stimulation, installation of positive cognitions, body scan, closure, and reevaluation. Outcomes were assessed at baseline, immediately post-intervention, and at one-month follow-up.

Behavioral: EMDR

Waitlist Control

NO INTERVENTION

Participants in this arm did not receive active psychological intervention during the study period and continued with usual care, if any. They completed the same outcome assessments at baseline, immediately after the intervention period for the EMDR group, and at one-month follow-up. After completion of all study assessments, participants in the waitlist control arm were offered the opportunity to receive EMDR therapy.

Interventions

EMDRBEHAVIORAL

Participants received Eye Movement Desensitization and Reprocessing (EMDR) therapy, a structured trauma-focused psychotherapy delivered individually by a licensed psychiatric mental-health professional trained in the standardized EMDR protocol. Sessions lasted approximately 90 minutes and were conducted three times per week over the intervention period. The protocol followed the established EMDR phases, including history taking, preparation, identification of target memories, bilateral stimulation (e.g., guided eye movements or alternating taps), installation of adaptive cognitions, body scan, closure, and reevaluation. Outcomes were measured at baseline, immediately post-intervention, and at one-month follow-up.

EMDR Therapy Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 18 years or older
  • Probable PTSD or moderate-to-severe post-traumatic stress symptoms based on the screening instrument used in the study
  • Exposure to at least one traumatic or highly stressful life event within the previous six months
  • No prior receipt of EMDR therapy
  • Willingness and ability to provide informed consent and participate in therapy sessions and assessments

You may not qualify if:

  • Acute cognitive or intellectual disability that would interfere with comprehension of study procedures or questionnaires
  • Significant visual impairment or visual pathology that would prevent full engagement with the visual components of EMDR therapy
  • Inability to communicate effectively by phone for scheduled assessments
  • Refusal or inability to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Nursing

Amman, Aljubeiha, 11942, Jordan

Location

MeSH Terms

Conditions

Combat DisordersStress Disorders, Post-Traumatic

Interventions

Eye Movement Desensitization Reprocessing

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Desensitization, PsychologicBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Ayman M. Hamdan-Mansour, Professor

    The University of Jordan

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Masking Details
No masking was implemented. Participants, intervention providers, and outcome assessors were aware of group allocation throughout the study.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: This study used a two-arm parallel assignment design in which eligible participants were allocated to either an EMDR intervention group or a waitlist control group. Outcomes were assessed at baseline, immediately post-intervention, and at one-month follow-up. Participants in the control arm did not receive active treatment during the study period but were offered EMDR therapy after completion of outcome assessments. No crossover between groups occurred during the trial.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assisstant professor

Study Record Dates

First Submitted

February 14, 2026

First Posted

February 20, 2026

Study Start

March 15, 2023

Primary Completion

December 25, 2023

Study Completion

February 14, 2024

Last Updated

February 20, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be publicly shared due to privacy, confidentiality, and ethical considerations related to the sensitive mental-health information collected. Data may be made available in a de-identified and aggregated form upon reasonable request to the corresponding author and subject to institutional ethics approval and data-use agreements.

Locations