NCT07421570

Brief Summary

The aim of this study is to evaluate the effects of capacitive resistive electric transference (CRET), which is frequently used in clinics and sports clubs for professional soccer players with hamstring injuries. We thought that CRET could have positive effects on tissue healing in the subacute phase of hamstring injuries.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 10, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

February 12, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 19, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2026

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 20, 2026

Completed
Last Updated

February 19, 2026

Status Verified

February 1, 2026

Enrollment Period

2 months

First QC Date

February 12, 2026

Last Update Submit

February 12, 2026

Conditions

Hamstring Injury

Keywords

rehabilitationhamstringstrain

Outcome Measures

Primary Outcomes (1)

  • Return to Sport Time

    The primary outcome measure is the number of days from the time of injury to the time when criteria for full return to sports are met.

    5 weeks

Secondary Outcomes (3)

  • Hamstring Flexibility

    5 weeks

  • Hamstring strength

    5 weeks

  • Muscle Oxygen Saturation (NIRS)

    5 weeks

Study Arms (2)

CRET experimental

EXPERIMENTAL

In addition to the standard rehabilitation program, the experimental group will receive CRET therapy (T-Plus; Wintecare SA, Chiasso, Switzerland) at the end of each session.

Device: T-Plus; Wintecare SA, Chiasso, SwitzerlandOther: Exercise

Control

ACTIVE COMPARATOR

Participants in the control group will undergo a standard, evidence-based, three-stage hamstring rehabilitation program.

Other: Exercise

Interventions

T-Plus; Wintecare SA, Chiasso, SwitzerlandDEVICE

Experimental Group (CRET Therapy): In addition to the standard rehabilitation program, CRET therapy (T-Plus; Wintecare SA, Chiasso, Switzerland) will be applied at the end of each session to the experimental group. Positioning: The athlete will be placed in a prone position, with the passive electrode placed under the quadriceps muscle and the active electrode applied in the direction of the hamstring muscle fibers using classic massage maneuvers. Dosage and Duration: The treatment will last a total of 20 minutes, consisting of 10 minutes in resistive mode followed by 10 minutes in capacitive mode. Intensity: The application will start at 70% intensity. If the thermal sensation reaches a level that disturbs the athlete, the intensity will be gradually reduced by 10% to achieve the maximum tolerable thermal effect.

CRET experimental
ExerciseOTHER

A standard hamstring rehabilitation program consisting of three phases will be implemented.

CRET experimentalControl

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • History of acute onset hamstring pain.
  • Grade I or II hamstring strain injury confirmed by Magnetic Resonance Imaging (MRI) within the first 5 days following the injury.
  • No history of anterior cruciate ligament (ACL) reconstruction.

You may not qualify if:

  • Presence of neurological symptoms.
  • Loss of superficial sensation or skin pathologies that may prevent CRET application.
  • Refusal to sign the approval form.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, Altindag, 06100, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Sprains and Strains

Interventions

Exercise

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Irem DUZGUN

    Hacettepe University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Irem DUZGUN, PHD

CONTACT

+90 532 477 40 00iremduzgun@hacettepe.edu.tr

Baran Akay, MD

CONTACT

+90 535 891 44 03baranakay@icloud.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
Neither the participants nor the physiotherapist conducting the assessment will be aware of which groups the participants belong to.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Two groups including control and experimental groups
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Irem Duzgun

Study Record Dates

First Submitted

February 12, 2026

First Posted

February 19, 2026

Study Start

February 10, 2026

Primary Completion

April 15, 2026

Study Completion

April 20, 2026

Last Updated

February 19, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)