Effect of Different HPV Education Methods on Vaccination Intention in Young Women

NCT07420556 | Recruiting

• 1 other identifier: HPV-EDU-2026-RCT
• Study Type: interventional
• Target: 117
• Locations: 1 country
• Sites: 1

Brief Summary

Detailed Description Human papillomavirus (HPV) is one of the leading causes of cervical cancer and can be prevented by vaccination. However, HPV vaccination rates among young women are low, largely due to insufficient knowledge and misconceptions about HPV and the vaccine. Therefore, an effective educational program may improve both knowledge and vaccination intention. The aim of this randomized controlled trial is to examine the effect of delivering HPV education through different methods (asynchronous online education delivered via a pre-recorded video and face-to-face education) on HPV knowledge level and HPV vaccination intention among women aged 18-24 years. The study will be conducted with women aged 18-24 years registered at Family Health Centers in the Afşin district of Kahramanmaraş, Türkiye. Eligible participants will be randomly assigned into three groups: the video-based education group, the face-to-face education group, and the control group. Data will be collected using the Participant Information Form, HPV Knowledge Scale, and HPV Vaccination Attitude and Intention Form. Measurements will be performed at three time points: before the education (pre-test), immediately after the education (post-test), and one month after the education (follow-up test). The video-based education group will receive the education via a pre-recorded online video, while the face-to-face group will receive the same content in person at the Family Health Center. No education will be provided to the control group; only measurements will be obtained. Research Questions Does HPV education delivered through different methods increase HPV knowledge levels among young women? Does HPV education increase HPV vaccination intention compared with the control group? Is face-to-face education more effective than video-based education in increasing vaccination intention? Are the improvements in knowledge and vaccination intention sustained one month after the education?

Conditions

Human Papillomavirus (HPV) Infection; HPV Vaccination Acceptance/Intention

Keywords

HPV; HPV vaccination; HPV vaccine acceptance; preventive health behavior; health education

Outcome Measures

Primary Outcomes (1)

• HPV Knowledge and Vaccination Intention - Pre-Test

  Young women who consent to participate in the study will complete the Participant Information Form and the HPV Knowledge and Vaccination Intention Scale before receiving any education. This stage aims to determine participants' baseline knowledge and intention to vaccinate.

  Before education

Secondary Outcomes (2)

• HPV Knowledge and Vaccination Intention - Post-Education Test

  Immediately after education

• HPV Knowledge and Vaccination Intention - 1-Month Follow-Up Test

  : 1 month after education

Study Arms (3)

Control Group

NO INTERVENTION

Participants in this group will not receive any HPV education during the study period and will complete the same assessments as the intervention groups at all measurement time points.

Video-Based Education Group

EXPERIMENTAL

Participants in this group will receive HPV and HPV vaccination education delivered through a standardized educational video prepared in accordance with national health guidelines.

Behavioral: Video-Based HPV Education

Face-to-Face Education Group

EXPERIMENTAL

Participants in this group will receive HPV and HPV vaccination education through face-to-face training provided by the researcher using standardized educational materials.

Behavioral: Face-to-Face HPV Education

Interventions

Video-Based HPV Education BEHAVIORAL

A structured educational video providing information about HPV infection, transmission, prevention, and HPV vaccination.

Video-Based Education Group

Face-to-Face HPV Education BEHAVIORAL

A structured face-to-face educational session conducted by the researcher covering HPV infection, transmission, prevention, and HPV vaccination.

Face-to-Face Education Group

Eligibility Criteria

• Age: 18 Years - 24 Years
• Gender Eligibility Details: Only individuals who are biologically female, identify as female, and are aged 18-24 years are eligible to participate in the study.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants must meet all of the following criteria to be included in the study:
• Aged 18-24 years,
• Residing in Afşin district, Kahramanmaraş province,
• Willing to voluntarily participate in the study,
• Literate and able to understand survey questions in Turkish,
• Have not previously received the HPV vaccine,
• Agree to be available throughout the study period (pre-test, post-education test, and 1-month follow-up test),
• Young women without physical or cognitive impairments or serious health problems that would prevent participation in the study.

You may not qualify if:

• Participants will be excluded if they meet any of the following conditions:
• Under 18 or over 24 years of age,
• Have received the HPV vaccine or started the vaccine series,
• Have been diagnosed with HPV infection,
• Unable to attend the educational sessions or complete all stages of data collection (pre-test, post-education test, 1-month follow-up test),
• Illiterate or unable to understand the study forms in Turkish,
• Withdraw from the study or indicate unwillingness to continue participation,
• Have serious hearing, vision, or cognitive impairments that would prevent meaningful engagement in the educational sessions.

Sponsors & Collaborators

• Emel GÜÇLÜ CİHAN: lead
• Kahramanmaras Sutcu Imam University: collaborator

Study Sites (1)

Afşin Aile Sağlığı Merkezleri

Kahramanmaraş, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Papillomavirus Infections; Infections; Health Education

Condition Hierarchy (Ancestors)

Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Communicable Diseases; DNA Virus Infections; Virus Diseases; Tumor Virus Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Adherence Interventions; Medication Adherence; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Central Study Contacts

Emel Asst. Prof.

CONTACT

03443004913; emel_guclu4606@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Masking was not possible due to the nature of the intervention; this is an open-label study.
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Participants will be randomly assigned to one of three parallel groups: a control group, a video-based education group, or a face-to-face education group. Each participant will remain in the assigned group throughout the study, and outcomes will be compared between groups across three measurement time points (baseline, immediately after the intervention, and one-month follow-up).

Study Record Dates

• First Submitted: February 12, 2026
• First Posted: February 19, 2026
• Study Start: December 15, 2025
• Primary Completion: January 15, 2026
• Study Completion: March 31, 2026
• Last Updated: February 19, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)