My Path to Quit Tobacco
Comparing Three Multicomponent Interventions to Help Adults Quit Smoking
4 other identifiers
interventional
1,550
1 country
5
Brief Summary
The overarching goal of this program of research is to reduce smoking-related health disparities by increasing smoking cessation among Black adults. The goal of this research proposal is to determine whether more intensive, culturally specific, evidence-based interventions are more effective at promoting long-term cessation and other key patient-centered outcomes compared to the usual evidence-based standard of care: services provided by a state-run quitline. This study compares the relative effectiveness of three different treatments (Standard, Intensive, and Intensive Incentivized) on long-term smoking cessation (biochemically confirmed abstinence from combusted tobacco at 26-weeks post-target quit day) among Black adults who smoke and want to quit.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_4
Started Jun 2026
Longer than P75 for phase_4
5 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 11, 2026
CompletedFirst Posted
Study publicly available on registry
February 19, 2026
CompletedStudy Start
First participant enrolled
June 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 1, 2030
May 6, 2026
May 1, 2026
3.6 years
February 11, 2026
May 4, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Biochemically confirmed abstinence from combusted tobacco at 26-weeks post-target quit day
The primary outcome for this study will be biochemically confirmed (anabasine less than 2 ng/ml) 7-day point-prevalence smoking abstinence at 26- weeks post-TQD
26 weeks post-TQD
Secondary Outcomes (7)
Biochemically confirmed abstinence from any nicotine product at 26-weeks post-target quit day
26 weeks post-TQD
Treatment Satisfaction
8 weeks post-TQD
Cigarettes per day
baseline, 8 and 26 weeks post-TQD
Quality of Life measured by the Medical Outcomes Study's 12-item Short Form Survey Instrument (SF-12)
baseline, 8 and 26 weeks post-TQD
Money spent on cigarettes per week
baseline, 8 and 26 weeks post-TQD
- +2 more secondary outcomes
Study Arms (3)
Standard Intervention
ACTIVE COMPARATORThe Standard Intervention will include 2 weeks of nicotine patches + 4 quitline-style counseling phone calls.
Intensive Intervention
EXPERIMENTALThe Intensive Intervention will include 8 weeks of nicotine patches (if eligible) + 8 counseling sessions (choice of individual phone or virtual group) + the Pathways to Freedom video content on the study website with additional smoking cessation content.
Intensive Incentivized Intervention
EXPERIMENTALThe Intensive Incentivized Intervention will include all components provided in the Intensive intervention (8 weeks of nicotine patches (if eligible) + 8 counseling sessions (choice of individual phone or virtual group) + the Pathways to Freedom video content on the study website with additional smoking cessation content) and up to $50 for completing counseling sessions ($5 for completing sessions 1-6 and $10 for completing sessions 7 and 8)
Interventions
Pathways to Freedom video content, a 60-minute video that addresses key issues such as emotional dependence, nicotine replacement, identifying smoking triggers, developing coping skills, and other behavioral strategies people can use to support a quit attempt.
Patch dosing will be consistent with the package insert
4, 10 to 15-minute counseling sessions (the duration of a typical quitline call) will occur via phone one week prior to the TQD, 1 day after the TQD, and 1 and 2 weeks after the TQD.
Participants will have the option of choosing 8, 30-minute counseling phone calls or 8, 60-minute video group counseling sessions
up to $50 for completing counseling sessions ($5 for completing sessions 1-6 and $10 for completing sessions 7 and 8)
Eligibility Criteria
You may qualify if:
- self-identify as Black
- smoke cigarettes (greater than or equal to 1 cigarette on greater than or equal to 4 days/week)
- motivated to quit smoking
- willing to discontinue any non-study smoking cessation pharmacotherapy use during study treatment.
You may not qualify if:
- currently taking bupropion for non-smoking cessation reasons
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (5)
Arizona State University
Phoenix, Arizona, 85004, United States
Indiana University
Indianapolis, Indiana, 46202, United States
University of Kansas Medical Center Research Institute, Inc
Kansas City, Kansas, 66160, United States
Virginia Commonwealth University
Richmond, Virginia, 23298, United States
UW School of Medicine and Public Health
Milwaukee, Wisconsin, 53233, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Megan Piper, PhD
UW School of Medicine and Public Health
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 11, 2026
First Posted
February 19, 2026
Study Start
June 1, 2026
Primary Completion (Estimated)
January 1, 2030
Study Completion (Estimated)
January 1, 2030
Last Updated
May 6, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF