Correlation of Ultrasound-Measured Detrusor and Bladder Wall Thickness With Urodynamic Parameters in Spinal Cord Injury

NCT07419165 | Completed

• 1 other identifier: 2-24-12
• Study Type: observational
• Target: 116
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the correlation between detrusor and bladder wall thickness measured by suprapubic ultrasound and urodynamic parameters in patients with spinal cord injury. By evaluating ultrasonographic measurements alongside urodynamic findings, the study seeks to assess their relationship in a prospective cross-sectional setting.

Conditions

Spinal Cord Injury; Neurogenic Lower Urinary Tract Dysfunction

Keywords

Spinal Cord Injury; Neurogenic lower urinary tract dysfunction; Bladder wall thickness; Urodynamic studies; Ultrasonography

Outcome Measures

Primary Outcomes (1)

• Correlation between ultrasound-measured detrusor and bladder wall thickness and urodynamic parameters

  The association between suprapubic ultrasound-measured bladder wall thickness and detrusor wall thickness and urodynamic parameters, including cystometric capacity, maximum cystometric capacity, maximum detrusor pressure, leak point pressure, bladder capacity at the time of leakage, total leakage volume, bladder compliance, presence of bladder sensation, presence of detrusor overactivity, presence of sphincter hyperactivity, maximum flow rate, detrusor pressure at maximum flow, voided volume, and postvoid residual urine volume.

  Ultrasonographic measurements were performed during the same clinical evaluation period, either on the same day as or within one day prior to the urodynamic study.

Secondary Outcomes (1)

• Association of bladder and detrusor wall thickness with clinical characteristics

  During the same clinical evaluation period as the urodynamic study, either on the same day as or one day prior to urodynamic testing.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with spinal cord injury admitted to the inpatient rehabilitation program at Ankara Bilkent City Hospital Physical Therapy and Rehabilitation Hospital, referred to the Urodynamy Laboratory, who met the inclusion criteria and consented to participate in the study.

You may qualify if:

• ≥18-65 years of age
• Traumatic and non-traumatic SCI
• Willingness to participate and able to provide written informed consent

You may not qualify if:

• Neurogenic lower urinary tract dysfunction not caused by spinal cord injury
• History of brain surgery
• History of augmentative urinary surgery or invasive bladder procedures (e.g., bladder tumor resection, botulinum toxin injection)
• History of urinary tract malignancy
• Prior overactive bladder or urinary incontinence, or prior surgery for benign prostatic hyperplasia
• Bladder outlet obstruction
• Cognitive impairment that would interfere with participation
• Active urinary tract infection preventing urodynamic evaluation

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Çankaya, 06800, Turkey (Türkiye)

Location

Related Publications (2)

• Pannek J, Bartel P, Gocking K, Frotzler A. Clinical usefulness of ultrasound assessment of detrusor wall thickness in patients with neurogenic lower urinary tract dysfunction due to spinal cord injury: urodynamics made easy? World J Urol. 2013 Jun;31(3):659-64. doi: 10.1007/s00345-012-0970-6. Epub 2012 Oct 17.

  PMID: 23073657 BACKGROUND

• Silva JA, Gonsalves Mde C, de Melo RT, Carrerette FB, Damiao R. Association between the bladder wall thickness and urodynamic findings in patients with spinal cord injury. World J Urol. 2015 Jan;33(1):131-5. doi: 10.1007/s00345-014-1265-x. Epub 2014 Feb 27.

  PMID: 24573904 BACKGROUND

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Hakan Tunç, Professor doctor

  Ankara City Hospital Bilkent

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 19, 2026
• First Posted: February 18, 2026
• Study Start: February 21, 2024
• Primary Completion: October 1, 2025
• Study Completion: October 1, 2025
• Last Updated: February 18, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)