NCT07412964

Brief Summary

Sleep disruption is common in adult intensive care unit (ICU) patients and is often worsened by environmental noise and nighttime care activities. Poor sleep may negatively affect recovery and well-being. This single-center, three-arm randomized controlled trial will evaluate the short-term effects of two non-pharmacological interventions-(1) pink-brown noise masking and (2) a quiet time intervention-on objective sleep parameters in adult ICU patients, compared with standard care. Sleep outcomes will be measured using actigraphy-based wearable monitoring, including total sleep time, sleep efficiency, sleep onset latency, wake after sleep onset, and number of awakenings. Results are expected to support evidence-based nursing approaches to improve sleep in ICU patients.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
7mo left

Started May 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress9%
May 2026Jan 2027

First Submitted

Initial submission to the registry

February 4, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 17, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

May 1, 2026

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2027

Last Updated

April 22, 2026

Status Verified

April 1, 2026

Enrollment Period

8 months

First QC Date

February 4, 2026

Last Update Submit

April 17, 2026

Conditions

Keywords

Intensive Care UnitsNoiseSound MaskingActigraphySleep Disturbance

Outcome Measures

Primary Outcomes (1)

  • Sleep Efficiency

    Sleep efficiency will be measured using a single wrist-worn actigraphy device (smartwatch) during nighttime sleep (23:00-06:00).

    Single night (23:00-06:00)

Secondary Outcomes (4)

  • Total Sleep Time

    Single night (23:00-06:00)

  • Sleep Onset Latency

    Single night (23:00-06:00)

  • Wake After Sleep Onset

    Single night (23:00-06:00)

  • Number of Nocturnal Awakenings

    Single night (23:00-06:00)

Study Arms (3)

Acoustic Noise Masking Group

EXPERIMENTAL

Patients receiving environmental acoustic noise masking before and during nighttime sleep.

Behavioral: Acoustic Noise Masking Intervention

Quiet Night Intervention Group

ACTIVE COMPARATOR

Patients receiving a quiet night protocol including environmental noise and light reduction supported by earplugs and eye mask.

Behavioral: Quiet Night Intervention

Standard Care Control Group

NO INTERVENTION

Patients receiving routine intensive care without additional sleep-promoting interventions.

Interventions

Environmental acoustic noise masking applied before and during nighttime sleep to reduce ambient ICU noise and support sleep continuity.

Acoustic Noise Masking Group

A quiet night protocol including environmental noise and light reduction supported by earplugs and an eye mask.

Quiet Night Intervention Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults aged 18 years and older
  • Patients admitted to the adult intensive care unit
  • Expected ICU stay of at least one night
  • Ability to tolerate non-invasive sleep-related interventions (earplugs, eye mask, or acoustic masking)
  • Informed consent obtained from the patient or legally authorized representative

You may not qualify if:

  • Severe hearing impairment preventing use of acoustic interventions
  • Severe cognitive impairment or coma preventing sleep assessment
  • Use of continuous deep sedation
  • Diagnosed sleep disorders requiring pharmacological treatment
  • Skin conditions preventing use of wrist-worn actigraphy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bolu Izzet Baysal State Hospital

Bolu, Bolu, 14100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Parasomnias

Condition Hierarchy (Ancestors)

Sleep Wake DisordersNervous System DiseasesMental Disorders

Central Study Contacts

Saadet Can Çiçek, Assoc. Prof., PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessors and data analysts are blinded to group allocation. Participants and care providers are not blinded due to the nature of the interventions.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: This is a single-center, three-arm, parallel-group randomized controlled trial. Participants are randomly assigned to one of three groups: an acoustic noise-masking intervention group, a quiet night intervention group, or a standard care control group. Each participant receives only the assigned intervention.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 4, 2026

First Posted

February 17, 2026

Study Start

May 1, 2026

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

January 1, 2027

Last Updated

April 22, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared publicly. De-identified data may be made available upon reasonable request to the corresponding investigator, subject to ethical approval and institutional regulations.

Locations