Study of the Effectiveness of a Systematic Minimal Early Intervention on Care Engagement in Adults With Eating Disorders Requesting Specialized Treatment.

NCT07411807 | Recruiting

• 2 other identifiers: D24-P0282025-A00104-45
• Study Type: interventional
• Target: 215
• Locations: 1 country
• Sites: 1

Brief Summary

Eating disorders (EDs) are complex psychiatric conditions-such as anorexia nervosa and bulimia nervosa-often emerging in young adulthood and associated with high morbidity and mortality. Despite their severity, access to specialized care remains difficult, delayed by shame, stigma, and a lack of insight among patients, as well as long waiting times and limited specialized resources. The AGIS-TCA pilot study aims to evaluate the effectiveness of a systematic minimal early intervention designed to reduce the number of patients lost to follow-up between their request for specialized care and the actual start of treatment. This monocentric, low-risk interventional study will be conducted at the Clinique des Maladies Mentales et de l'Encéphale (CMME), GHU Paris Psychiatrie \& Neurosciences. The intervention includes three early, structured telephone calls and five online support group sessions offered during the waiting period for care. The main objective is to determine whether this proactive approach decreases attrition rates ("lost to follow-up") compared with a historical cohort. Secondary objectives include assessing the acceptability of early phone contact, adherence to support groups, and describing the clinical and sociodemographic profiles of patients requesting care or lost to follow-up. The expected benefit is to facilitate timely access to care for vulnerable patients, prevent symptom worsening, and strengthen engagement in treatment pathways. Risks and constraints are minimal, as participation involves only remote interactions without any invasive procedures.

Conditions

Eating Disorders

Keywords

Anorexia Nervosa, Bulimia Nervosa

Outcome Measures

Primary Outcomes (1)

• Rate of Patients Lost to Follow-Up

  The primary outcome is the difference in the rate of patients lost to follow-up between the intervention group (AGIS-TCA program) and a historical control cohort. A patient is considered lost to follow-up if they have submitted a valid request for specialized care (excluding cases of reorientation) but have not attended the evaluation days at the Eating Disorders Expert Center (CMME) or completed their intake process within 10 months of their initial request.

  7 months

Secondary Outcomes (4)

• Adherence to Online Support Groups

  At the end of the 3-month

• Acceptability of Early Telephone Contact

  first 7 days

• Clinical and Sociodemographic Profile of Patients Requesting Specialized Care

  the 6-month

• Clinical and Sociodemographic Profile of Patients Lost to Follow-Up

  end of the 10-month

Study Arms (2)

AGIS-TCA Intervention Group

EXPERIMENTAL

Participants will receive a systematic minimal early intervention designed to maintain engagement during the waiting period before specialized treatment for an eating disorder. The intervention includes: Three structured telephone calls (AT1, AT2, AT3) at approximately day 7, day 45, and day 90 after validation of the care request. These calls aim to provide information, emotional support, and risk prevention guidance, and to maintain motivation for treatment. Five online support group sessions (60 minutes each, every two weeks) led by a multidisciplinary team (specialized nurse, physician, dietitian, psychologist, psychomotor therapist, and peer support worker). Duration: 3 months per participant. Number of Participants: 215 adults. Study Site: Clinique des Maladies Mentales et de l'Encéphale (CMME), GHU Paris Psychiatrie \& Neurosciences.

Other: Program (Systematic Minimal Early Intervention for Eating Disorders)

Historical Comparison Group

NO INTERVENTION

A historical cohort of patients who requested specialized care for an eating disorder during the previous year (01/11/2024-31/10/2025), before implementation of the AGIS-TCA program. These patients received standard care procedures, which involved no systematic contact during the waiting period between their request for treatment and the start of care.

Interventions

Program (Systematic Minimal Early Intervention for Eating Disorders) OTHER

The AGIS-TCA intervention consists of a structured early proactive support program designed to maintain patient engagement during the waiting period before specialized treatment for eating disorders

AGIS-TCA Intervention Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individual who has submitted a request for care to the CMME for an eating disorder (anorexia nervosa or bulimia)
• Adult (18 years or older) Resident of the Île-de-France region

You may not qualify if:

• Body mass index (BMI) greater than 30 kg/m²: these patients will be directed, from the first telephone contact, to structures or care networks that can offer appropriate treatment.
• Poor understanding of the French language
• Sensory impairment significantly affecting telephone communication
• Patient currently receiving care at a specialized eating disorder facility at the time of the call
• Patient not consenting to participate in the study
• Subject under legal protection measures (guardianship or curatorship)

Sponsors & Collaborators

• Centre Hospitalier St Anne: lead

Study Sites (1)

GHU Paris Psychiatrie et Neurosciences

Paris, 75014, France

RECRUITING

MeSH Terms

Conditions

Feeding and Eating Disorders; Anorexia Nervosa; Bulimia Nervosa

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Officials

• MARION Mme DELOULAY, Nurse

  Hôpital Sainte-Anne

  PRINCIPAL INVESTIGATOR

Central Study Contacts

OUIZA Mme MANSEUR, PROJECT MANAGER

CONTACT

01.45.65.61.65; ouiza.manseur@ghu-paris.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 9, 2026
• First Posted: February 17, 2026
• Study Start: December 29, 2025
• Primary Completion (Estimated): April 1, 2027
• Study Completion (Estimated): April 1, 2027
• Last Updated: February 17, 2026

Record last verified: 2026-02

Locations

FR (1)