NCT07411729

Brief Summary

This multicenter prospective registry aims to establish a biobank of residual biological samples and associated clinical data from hospitalized patients. The registry will collect a wide range of specimens (serum, plasma, respiratory samples, urine, cerebrospinal fluid, biopsies) obtained during routine care, without any additional procedures. Data are pseudonymized and stored securely for up to 20 years. The biobank will be used to develop and evaluate rapid diagnostic tests (RDTs) for emerging infectious diseases and CBRN threats to improve epidemic preparedness and patient management.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
800

participants targeted

Target at P75+ for all trials

Timeline
1mo left

Started Jun 2024

Geographic Reach
1 country

10 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress94%
Jun 2024Jun 2026

Study Start

First participant enrolled

June 3, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

February 9, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 17, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Last Updated

February 17, 2026

Status Verified

January 1, 2026

Enrollment Period

2 years

First QC Date

February 9, 2026

Last Update Submit

February 9, 2026

Conditions

Keywords

Blood and blood derivatives: whole blood, serum, plasma, cord bloodMicrobiological specimens: positive blood culturesUrine samplesRespiratory samplesexpectorationsbronchoalveolar lavage (BAL)protected distal samplesbronchial aspirationsCerebrospinal fluidStool or rectal swabsSkin or mucosal swabsBiopsies and puncture material: lymph node, hepatic, gastric, or other tissue samples when available

Outcome Measures

Primary Outcomes (1)

  • Number of residual clinical samples successfully collected, aliquoted, and stored with associated clinical and microbiological data

    Creation of a collection of residual biological samples (serum, plasma, urine, respiratory samples, CSF, biopsies, etc.) and associated clinical and microbiological data obtained during routine care

    36months (end of patient inclusion period)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients hospitalized in one of the participating study centers

You may qualify if:

  • Adults (≥ 18 years old) hospitalized in one of the participating centers at Bicêtre or Paul Brousse hospitals, for whom residual biological samples are available as part of routine care in one or more participating hospital departments.
  • Covered by, or entitled to, the French social security system (excluding State Medical Aid - AME).
  • Patient or legal representative/trusted person informed about the registry and having provided written consent to participate.

You may not qualify if:

  • Patients under judicial protection (guardianship or curatorship).
  • Patients deprived of liberty by judicial or administrative decision.
  • Patients not speaking French and not accompanied by a translator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Bicêtre

Le Kremlin-Bicêtre, France

RECRUITING

CHU Paul Brousse

Villejuif, France

RECRUITING

MeSH Terms

Conditions

Communicable Diseases, EmergingCommunicable DiseasesZoonoses

Condition Hierarchy (Ancestors)

InfectionsDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsAnimal Diseases

Central Study Contacts

Thierry NAAS,, PhD

CONTACT

Saoussen OUESLATI, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 9, 2026

First Posted

February 17, 2026

Study Start

June 3, 2024

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

February 17, 2026

Record last verified: 2026-01

Locations