Trials Sponsors Conditions Drugs Pricing

Conditions

Lumbar Herniated Disk Lumbar Radiculopathy

Keywords

steroidslumbar radiculopathyback and leg painODIendoscopic surgery

Outcome Measures

Primary Outcomes (1)

NRS back and NRS leg
back and leg pain measured by a numerical rating scale. the NRS is a 0 to 10 scale in which 10 means the highest pain score
patients will be evaluated over a 3 month period postoperatively, first at 48 hours post surgery, then 2 weeks and 1 month after surgery.

Secondary Outcomes (1)

ODI
patients will be evaluated over a 3 month period postoperatively, first at 1 month and then 3 months.

Study Arms (2)

control group

ACTIVE COMPARATOR

Patients undergoing full-endoscopic lumbar discectomy receiving epidural saline.

Other: Control group (Normal Saline) (C)

Dexamethasone group

EXPERIMENTAL

Patients undergoing full-endoscopic lumbar discectomy receiving epidural dexamethasone 8 mg.

Drug: Intervention Group

Interventions

Intervention GroupDrug

patients given intraoperative dexamethasone after hernia removal

Dexamethasone group

Control group (Normal Saline) (C)Other

patients given 2mL saline

control group

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Adult patients (≥18 years) Undergoing single-level full-endoscopic lumbar discectomy Symptomatic lumbar disc herniation Ability to provide written informed consent

You may not qualify if:

Sponsors & Collaborators

Centro Hospitalar De São João, E.P.E.
Otherlead

Study Sites (1)

Centro Hospitalar Universitario São João

Porto, Porto District, 4445, Portugal

MeSH Terms

Conditions

RadiculopathyIntervertebral Disc Displacement

Interventions

Control GroupsSaline Solution

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesSpinal DiseasesBone DiseasesMusculoskeletal DiseasesHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Enrollment

90 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: DOUBLE
Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Principal Investigator

Study Record Dates

First Submitted

April 21, 2025

First Posted

February 13, 2026

Study Start

September 10, 2022

Actual (reported)

Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

control group

Dexamethasone group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

control group

Dexamethasone group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations