Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section

NCT07406373 | Completed

• 1 other identifier: 2025/08-28
• Study Type: observational
• Target: 107
• Locations: 1 country
• Sites: 1

Brief Summary

Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during pregnancy. Increased intra-abdominal pressure and abdominal circumference may influence cerebrospinal fluid dynamics and affect the level of sensory block achieved after spinal anesthesia. This prospective observational study aims to evaluate the relationship between intra-abdominal pressure, abdominal circumference, and the maximum sensory block level following spinal anesthesia in pregnant women undergoing cesarean section. Intra-abdominal pressure and abdominal circumference will be measured before surgery, and sensory block levels and hemodynamic parameters will be assessed after spinal anesthesia. The findings of this study may help to better understand factors affecting spinal block spread in pregnant patients.

Conditions

Cesarean Section; Pregnancy; Elective Cesarean Section

Keywords

spinal block; obstetric anesthesia; sensory block level; spinal anesthesia; intra-abdominal pressure; abdominal circumference

Outcome Measures

Primary Outcomes (1)

• Maximum sensory block level after spinal anesthesia

  The maximum dermatomal level of sensory block assessed by loss of cold sensation after spinal anesthesia.

  Within the first 30 minutes after spinal anesthesia

Secondary Outcomes (4)

• Intra-abdominal pressure

  Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section)

• Abdominal circumference

  Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section)

• Incidence of hypotension after spinal anesthesia

  Within the first 30 minutes after spinal anesthesia

• Vasopressor requirement

  Perioperative period

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

This study includes pregnant women aged 18-40 years who were scheduled for elective cesarean section under spinal anesthesia at the Department of Obstetrics and Gynecology, Kütahya City Hospital. Eligible participants belonged to ASA physical status II-III and provided informed consent. The study population represents a clinically stable obstetric cohort undergoing elective cesarean delivery, without conditions known to significantly alter intra-abdominal pressure or spinal anesthesia characteristics.

You may qualify if:

• Pregnant women aged 18-40 years
• Scheduled for elective cesarean section at Kütahya City Hospital
• Planned spinal anesthesia
• ASA physical status II-III
• Provided written informed consent

You may not qualify if:

• Refusal to participate in the study
• Emergency cesarean section
• Preeclampsia or other hypertensive disorders of pregnancy
• Onset of labor or premature rupture of membranes
• Clinical conditions affecting intra-abdominal pressure, including peripheral edema or ascites
• Height \<140 cm or \>180 cm
• Body mass index \< 40 kg/m²
• Spinal deformity or history of spinal surgery
• Contraindications to neuraxial anesthesia
• Known allergy to bupivacaine
• Requirement for additional surgical procedures other than cesarean section
• Conditions contraindicating or interfering with intra-abdominal pressure measurement, including active or previous postdural puncture headache, neurogenic bladder, hematuria, or incidental abdominal mass

Sponsors & Collaborators

• Kutahya Health Sciences University: lead

Study Sites (1)

Kütahya Şehir Hastanesi

Kütahya, Kütahya, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 23, 2026
• First Posted: February 12, 2026
• Study Start: February 7, 2026
• Primary Completion: April 1, 2026
• Study Completion: April 30, 2026
• Last Updated: May 1, 2026

Record last verified: 2026-04

Locations

TU (1)