Head Up Position and Murottal Therapy in Stroke Patients

NCT07405593 | Not Yet Recruiting

• 1 other identifier: FDN-HU-MUROTTAL-STROKE-2026
• Study Type: interventional
• Target: 112
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on physiological and symptom outcomes in stroke patients. The intervention is expected to influence blood pressure, pulse rate, respiratory rate, pain level, and the incidence of projectile vomiting. Stroke patients will receive standard care with the addition of the combined intervention. The results of this study may support non-pharmacological nursing interventions to improve patient comfort and clinical stability.

Conditions

Stroke

Keywords

Head Up; Murottal Therapy

Outcome Measures

Primary Outcomes (5)

• Blood Pressure

  Change in systolic and diastolic blood pressure from baseline to after completion of the 3-day intervention.

  Baseline and after completion of the 3-day intervention

• Pulse Rate

  Change in pulse rate from baseline to after completion of the 3-day intervention.

  Baseline and after completion of the 3-day intervention

• Respiratory Rate

  Change in respiratory rate from baseline to after completion of the 3-day intervention

  Baseline and after completion of the 3-day intervention

• Pain Degree

  Change in pain score measured using the Critical-Care Pain Observation Tool (CPOT; range 0-8), where higher scores indicate more severe pain, from baseline to after completion of the 3-day intervention.

  Baseline and after completion of the 3-day intervention

• Projectile Vomiting

  Change in nausea and vomiting severity measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR; range 0-32), where higher scores indicate more severe symptoms, from baseline to after completion of the 3-day intervention.

  Baseline and after completion of the 3-day intervention

Study Arms (2)

Combination of 30-Degree Head-Up Positioning and Murottal Therapy

EXPERIMENTAL

Participants receive a combination of 30-degree head-up positioning and murottal therapy in addition to standard nursing care during the intervention period.

Other: Combination of 30 Degree Head Up and Murottal Therapy

Standard Care

ACTIVE COMPARATOR

Participants receive standard nursing care according to the hospital's clinical protocol without the addition of head-up positioning or murottal therapy.

Other: Standard Care (in control arm)

Interventions

Combination of 30 Degree Head Up and Murottal Therapy OTHER

Participants in this group received a combination of two non-pharmacological interventions during the study period. First, participants were positioned with their heads elevated at a 30-degree angle while lying in bed to support physiological stability, including monitoring of blood pressure, pulse rate, respiratory rate, pain level, and projectile vomiting. Second, participants listened to Quranic recitation (murottal therapy) via audio recording in a quiet environment. Both interventions were administered simultaneously. Intervention sessions lasted 30 minutes for 3 days (a consistent duration and frequency for all participants in this group). Outcomes such as vital signs, pain level, and episodes of severe vomiting were monitored before and after the intervention period.

Combination of 30-Degree Head-Up Positioning and Murottal Therapy

Standard Care (in control arm) OTHER

Participants in this arm receive standard nursing care according to the hospital protocol without additional head-up positioning or murottal therapy. Standard care includes routine monitoring of vital signs, medication administration, and basic supportive nursing interventions.

Standard Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with a medical diagnosis of stroke (hemorrhagic and non-hemorrhagic).
• Patients with systolic blood pressure above 150 mmHg.
• Somnolence (GCS ≥ 9).
• Muslim.
• Patients without hearing impairment.
• Willingness to participate and sign informed consent.

You may not qualify if:

• Patients who are non-Muslim.
• Patients with decreased consciousness (GCS \< 9).
• Patients with heart problems.
• Patients with psychiatric disorders.
• Patients receiving sedative therapy during the study.

Sponsors & Collaborators

• Universitas Muhammadiyah Surakarta: lead

Study Sites (1)

Rumah Sakit Indriati Solo Baru

Sukoharjo, Central Java, 57571, Indonesia

Location

Related Links

• Intracranial Pressure Monitoring and Management in Aneurysmal Subarachnoid Hemorrhage
• Adherence to Head-of-Bed Elevation in Traumatic Brain Injury: An Audit.
• Interdisciplinary Neurosurgery : Advanced Techniques and Case Management Position-dependent hemodynamic changes in neurosurgery patients : A narrative review.
• Nausea and vomiting in pregnancy ( NVP ) in Chinese pregnant women : a cross-sectional study
• Associations between computed tomography markers of cerebral small vessel disease and hemorrhagic transformation after intravenous thrombolysis in acute ischemic stroke patients.
• Blood Pressure Management Pre- and Post-Reperfusion in Acute Ischemic Stroke: Evidence and Insights from Recent Studies.
• Measuring pain intensity in older patients : a comparison of five scales.
• The Impact of Listening to , Reciting , or Memorizing the Quran on Physical and Mental Health of Muslims : Evidence From Systematic Review

MeSH Terms

Conditions

Stroke

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Central Study Contacts

Fila Diana Nurhayati, S.Kep.,Ns

CONTACT

+6281228527848; j218250001@student.ums.ac.id

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Masking Details: This study is conducted as an open-label trial because the non-pharmacological interventions, including 30-degree head-up positioning and murottal therapy, are clearly observable and cannot be feasibly blinded to participants, care providers, or investigators.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Graduate Researcher

Model Details: Participants are assigned in parallel to an intervention group receiving 30-degree head-up positioning and murottal therapy or to a control group receiving standard care.

Study Record Dates

• First Submitted: January 26, 2026
• First Posted: February 12, 2026
• Study Start: March 1, 2026
• Primary Completion: May 31, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: February 12, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

ID (1)