Operative Risk After Pancreatic Surgery in Patients With End Stage Renal Disease

NCT07405099 | Enrolling By Invitation

• 1 other identifier: 202107127RINB
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

End-stage renal disease (ESRD) patients often present risk factors for many surgical complications. The severity of renal failure and whether the patient is receiving renal replacement therapy are also related to the difficulty of pancreatic and other major surgeries, causing many ESRD patients to hesitate when choosing surgery. Therefore, this project aims to retrospectively collect basic data, preoperative and postoperative blood tests (blood cell counts, biochemistry, tumor markers, glucose-related, lipid-related), and preoperative and postoperative imaging examinations (CT, MRI, Ultrasound, PET scan, Endoscopy, etc.) of ESRD patients who underwent pancreatic surgery at our hospital.the investigators aim to compare whether surgical methods, severity of renal failure, use of renal replacement therapy, and lesion margin clearance rates affect the occurrence of surgical complications, length of hospital stay, length of ICU stay, re-operation rates or severe complications, medical costs, and related quality of life. This analysis is intended to understand and analyze the surgical prognosis, care priorities, common complications, and the management and outcomes of our team for ESRD patients undergoing pancreatic surgery, with the expectation of providing more diverse and specific treatment recommendations for these patients in the future.

Conditions

Pancreatic Neoplasms

Keywords

pancreatic surgery; end-stage renal disease; renal placement therapy

Outcome Measures

Primary Outcomes (1)

• Rate of clinically relevant POPF and Clavian Dindo IIIA or higher complication

  within 6 months after operation

Interventions

pancreatectomy PROCEDURE

Any operation demanding pancreatic parenchyma transaction

Eligibility Criteria

• Age: 20 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with end-stage renal disease and need pancreatic surgery

You may qualify if:

• Males or females aged between 20 and 75 years.
• Patients scheduled to undergo pancreatic surgery.

You may not qualify if:

• Patients under 20 or over 75 years of age at this hospital.
• Presence of other active malignancies prior to diagnosis.
• Minors, pregnant women, breastfeeding women, and patients with psychiatric disorders.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

MeSH Terms

Conditions

Pancreatic Neoplasms; Kidney Failure, Chronic

Interventions

Pancreatectomy

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Pancreatic Diseases; Endocrine System Diseases; Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Digestive System Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: February 4, 2026
• First Posted: February 12, 2026
• Study Start: January 1, 2016
• Primary Completion (Estimated): December 31, 2034
• Study Completion (Estimated): December 31, 2034
• Last Updated: February 27, 2026

Record last verified: 2026-02