Impact of a Nutritional Intervention Based on Moroccan Dietary Habits on the Glycemic Control of Type 2 Diabetics

NCT07404280 | Active Not Recruiting

• 1 other identifier: 153/2024/2026
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to learn if a nutritional intervention adapted to Moroccan dietary habits can improve blood sugar control in adults with Type 2 Diabetes. The main questions it aims to answer are:

• Does a personalized diet based on Moroccan culinary traditions improve long-term blood sugar levels (HbA1c)?
• How does this intervention affect daily blood sugar fluctuations measured as interstitial glucose?
• Does the intervention lead to changes in body measurements, such as weight and Body Mass Index (BMI)? Participants will:
• Wear a Continuous Glucose Monitor (CGM) to track sugar levels in real-time.
• Keep a detailed food diary of all foods and drinks consumed.
• Follow their usual diet for the first 7 days to establish a baseline.
• Receive personalized dietary advice specifically tailored to Moroccan food habits.
• Return for clinical check-ups at 14, 90, and 180 days for blood tests and body measurements.

Conditions

Type 2 Diabetes (T2DM)

Keywords

Type 2 Diabetes; Artificial Intelligence; Nutritional Intervention; Glycemic Control; Moroccan Dietary Habits; Precision Nutrition

Outcome Measures

Primary Outcomes (1)

• Change in Interstitial Glucose Levels

  Evaluation of the impact of the Moroccan-adapted nutritional intervention on daily glucose fluctuations. This is measured using a Continuous Glucose Monitoring (CGM) system to record real-time glucose data.

  Baseline (Day 0 to Day 7) compared to the final follow-up at Day 180.

Secondary Outcomes (5)

• Change in HbA1c

  Baseline (Day 0) and Day 180.

• Change in Body Mass Index (BMI)

  Baseline (Day 0) and Day 180.

• Change in Waist Circumference

  Baseline (Day 0) and Day 180.

• Change in Body Composition

  Baseline (Day 0) and Day 180.

• Dietary Adherence

  Baseline (Day 7) compared to Day 180.

Study Arms (1)

Experimental: Adapted Nutritional Intervention

EXPERIMENTAL

A single group of 50 Type 2 Diabetic patients will participate in a four-stage intervention over 180 days. * Phase 1 (Baseline): Participants will follow their usual, free diet for 7 days while monitored by Continuous Glucose Monitoring (CGM) and food diaries to establish a baseline. * Phase 2 (Intervention): Participants receive personalized nutritional directives specifically adapted to traditional Moroccan dietary habits and culinary practices. * Phase 3 (Follow-up): Continuous monitoring and periodic consultations (at Day 14, Day 90, and Day 180) to adjust the intervention, measure metabolic changes (HbA1c), and evaluate anthropometric parameters.

Behavioral: Moroccan-Adapted Nutritional Plan

Interventions

Moroccan-Adapted Nutritional Plan BEHAVIORAL

The intervention consists of a structured diet plan that integrates traditional Moroccan ingredients and cooking methods while optimizing for glycemic control. It involves: * Personalized meal planning based on individual food diaries. * Education on carbohydrate counting and portion sizes within the Moroccan culinary context. * Use of Continuous Glucose Monitoring (CGM) data to provide real-time feedback on how specific Moroccan meals affect the participant's glucose levels.

Experimental: Adapted Nutritional Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Confirmed diagnosis of T2D by a healthcare professional.
• Age 18 years or older.
• A glycated hemoglobin (HbA1c) level less than 10%.
• Capacity to provide informed written consent and follow the study procedures.

You may not qualify if:

• Non-diabetic subjects.
• Type 1 diabetes or secondary diabetes.
• Age younger than 18 years.
• Pregnancy or planned pregnancy during the study period.
• HbA1c level greater than 10%.
• Chronic renal insufficiency or hepatic disease.
• Pathologies of the digestive tract that affect nutrient absorption.
• Known food allergies requiring highly specific restricted diets.

Sponsors & Collaborators

• Avicenna Military Hospital: lead

Study Sites (1)

Avicenna Military Hospital of Marrakech

Marrakesh, Marrakech Safi, 40160, Morocco

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Hicham Baïzri

  Department of Endocrinology, Diabetology and Metabolic Diseases, Avicenne Military Hospital, Marrakech, Morocco

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD student

Study Record Dates

• First Submitted: February 5, 2026
• First Posted: February 11, 2026
• Study Start: October 1, 2024
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: February 12, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Data will be available beginning 6 months after publication of the results and ending 3 years after publication.
• Access Criteria: Data will be shared with researchers who provide a methodologically sound proposal and after signing a data access agreement to ensure ethical use and patient anonymity.

Locations

MO (1)