Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study

NCT07402577 | Recruiting

• 1 other identifier: I-4720925
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study generates information on the feasibility and acceptability of a 3-month ecological momentary assessment (EMA) protocol to assess chronic pain and opioid use in adolescent and young adult (AYA) sarcoma survivors.

Conditions

Sarcoma; Childhood Sarcoma of Soft Tissue

Outcome Measures

Primary Outcomes (7)

• Feasibility of recruitment

  Feasibility of recruitment will be based on number eligible per medical record

  Up to 12 months

• Feasibility of assessment

  will be indexed by number completing 80% of EMA assessments

  Up to 12 months

• Feasibility of recruitment

  will be indexed by number attending baseline interview

  up to 12 months

• Feasibility of recruitment

  will be indexed by retention throughout EMA period

  Up to 12 months

• Reasons for nonparticipation

  Semi structured qualitive interviews will focus on factors that influenced participation

  UP to 12 months

• Acceptability of EMA Study Design

  self-reported difficulty of participating in daily EMA surveys (0-19) .

  Up to 12 months

• Acceptability of EMA Design

  Acceptability of the protocol will be assessed by responses on the System Usability Scale - A 10 question scale from 1 to 5 with 1 being strongly disagree and 5 being strongly agree.

  Up to 12 months

Interventions

Non Intervention Study OTHER

Non intervention study

Eligibility Criteria

• Age: 12 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients younger than 70 years old who were diagnosed with sarcoma between the ages of 12-24 and have no evidence of disease and/or are enrolled in survivorship care.

You may qualify if:

• All genders between the ages of 12-24 (inclusive) at sarcoma diagnosis.
• Any age \< 70 at the time of study enrollment.
• No evidence of disease and/or enrolled in survivorship care.
• Clinically meaningful pain related to disease or its treatments at baseline (defined as 3 or greater on a 0-10 Numerical Rating Scale).
• Willing to attend the baseline appointment in person.
• Access to internet-capable smartphone.
• Access to internet on an occasional basis.
• Willing and able to complete Ecological Momentary Assessments (EMAs) on internet-capable smartphone for a 3-month period after enrollment.
• Ability to understand and provide informed consent/assent.

You may not qualify if:

• \* Currently receiving active cancer-directed therapy.
• Unable to read or fluently speak English.
• Determined by clinical staff to have preexisting or cancer-associated cognitive impairment that could interfere with study participation.
• Acutely suicidal (e.g. intent or plan) or, with unstable medical or psychiatric condition verified by licensed study staff.
• Characteristics related to inability to complete the study protocol.

Sponsors & Collaborators

• Roswell Park Cancer Institute: lead
• University at Buffalo: collaborator

Study Sites (1)

Roswell Park Comprehensive Cancer Center

Buffalo, New York, 14263, United States

RECRUITING

MeSH Terms

Conditions

Sarcoma

Condition Hierarchy (Ancestors)

Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Neoplasms

Study Officials

• Andrew Rogers

  Roswell Park

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Andrew Rogers

CONTACT

1-800-767-9355; Andrew.Rogers@roswellpark.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 11, 2026
• Study Start: March 30, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2028
• Last Updated: April 15, 2026

Record last verified: 2026-04

Locations

US (1)