NCT07399119

Brief Summary

Researchers will split the sixty healthy smokers in half. Thirty people will serve as a control group and will be asked to walk or jog at a controlled pace for twelve minutes as part of an aerobic exercise program. Separately, 30 people participated in an aerobic exercise session that lasted 12 minutes and involved walking or running at a pace that the participants themselves controlled. WHBM will be done both prior to and subsequent to physical activity. To determine how WHBM affects the experimental group's pre- and post-WHBM heart rates, SpO2, blood pressure, and VO2 max, this study will be conducted.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 10, 2025

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 15, 2026

Completed
17 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 10, 2026

Completed
Last Updated

February 10, 2026

Status Verified

February 1, 2026

Enrollment Period

8 months

First QC Date

January 15, 2026

Last Update Submit

February 9, 2026

Conditions

Keywords

wim hoffaerobic

Outcome Measures

Primary Outcomes (2)

  • HEART RATE

    The number of heartbeats in a minute

    12 weeks

  • Vo2 max

    oxygen consumption

    12 weeks

Study Arms (2)

CONTROL

ACTIVE COMPARATOR

Researchers took the first measurement at t=0 minutes after 5 minutes of their arrival to allow them to rest. The measurements included heart rate and SpO2 using an oximeter (Medical Rossmax) and blood pressure using a sphygmomanometer. Then they were asked to perform a 12-minute walk/jog with speed controlled by them and incline = 1. At 4 and 8 minutes, the speed was reduced to 2.0 on the treadmill, and vitals were taken again. At t= 12 minutes we stopped the treadmill, recorded the distance covered, and proceeded to measure the heart rate. SpO2, blood pressure, and VO2max were calculated using the Cooper's test formula (Alvero-Cruz et al., 2017). Participants were asked to rest for 4 minutes, and then another measurement of the vital signs (heart rate, SpO2, and blood pressure) was taken before they were dismissed.

Other: aerobic exercise where it included walking/ jogging with a controlled speed by the participant

wim hof breathing exercises

EXPERIMENTAL

applying breathing interventions

Other: aerobic exercise where it included walking/ jogging with a controlled speed by the participantOther: Wim Hof Breathing Method

Interventions

participants were asked to listen attentively to the given instruction using noise cancelling headphones for the given instructions. For 11 minutes, an audio for Wim Hof breathing method that is as follow. * Take a strong inhalation through the nose. * Let out a relaxed exhalation through the mouth. * Repeat for 30 breaths. * On the 30th breath, exhale and hold your breath for 30 seconds in the first round then 1 minute in the 2nd round and 1 and a half minutes for the 3rd round. * Take a deep breath in after the previous hold then hold it in for 15 seconds in the 3 rounds. * Let your breathing return to normal. These steps were repeated for 3 rounds. And participants were allowed to let go of their held breath and hold it again if they couldn't keep holding it for the asked time in the audio

CONTROLwim hof breathing exercises

participants were asked to listen attentively to the given instruction using noise cancelling headphones for the given instructions. For 11 minutes, an audio for Wim Hof breathing method that is as follow. * Take a strong inhalation through the nose. * Let out a relaxed exhalation through the mouth. * Repeat for 30 breaths. * On the 30th breath, exhale and hold your breath for 30 seconds in the first round then 1 minute in the 2nd round and 1 and a half minutes for the 3rd round. * Take a deep breath in after the previous hold then hold it in for 15 seconds in the 3 rounds. * Let your breathing return to normal. These steps were repeated for 3 rounds. And participants were allowed to let go of their held breath and hold it again if they couldn't keep holding it for the asked time in the audio

wim hof breathing exercises

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Males and females.
  • Age range between 18 and 25 years.
  • Adults who are healthy

You may not qualify if:

  • If they had:
  • Any systemic disorders.
  • Musculoskeletal, neuromuscular, or chronic respiratory conditions.
  • Females were menstruating

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

BAU

Beirut, Tariq EL Jedida, 11-5020, Lebanon

Location

Related Links

MeSH Terms

Interventions

Jogging

Intervention Hierarchy (Ancestors)

RunningLocomotionMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaExerciseMotor Activity

Study Officials

  • rami L abbass, professor

    BAU

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Model Details: stop watch - blood pressure monitoring
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Khaled Takey Ahmed - Associateprofessor

Study Record Dates

First Submitted

January 15, 2026

First Posted

February 10, 2026

Study Start

June 10, 2025

Primary Completion

February 1, 2026

Study Completion

February 1, 2026

Last Updated

February 10, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

measured data

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
Time Frame
5 months

Locations