Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults

NCT07398443 | Recruiting

• 2 other identifiers: 00000691R01CA289409
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.

Conditions

Behavioral Economics; Cannabis Smoking; Tobacco Smoking

Outcome Measures

Primary Outcomes (2)

• Change in self-reported cannabis craving

  This study utilizes a structured cannabis cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Cannabis craving will be assessed following neutral cue exposure and then cannabis cue exposure. The primary outcome will be change in cannabis craving.

  Up to 40 days post-baseline session

• Change in self-reported tobacco craving

  This study utilizes a structured tobacco cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Tobacco craving will be assessed following neutral cue exposure and then tobacco cue exposure. The primary outcome will be change in tobacco craving.

  Up to 40 days post-baseline session

Study Arms (1)

Cue Reactivity

EXPERIMENTAL

Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).

Behavioral: Cue Reactivity

Interventions

Cue Reactivity BEHAVIORAL

Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).

Cue Reactivity

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Males/females who are 18 to 25 years of age
• Young adults who currently smoke commercial tobacco cigarettes (≥1x weekly in the past 30 days and for the past six months)
• Young adults who currently smoke marijuana (≥4 times in past 30 days and at least weekly on average for the last six months)
• Participants must report purchasing their own tobacco and marijuana at least once in the past 6 months
• Participants must speak, comprehend, and read English.

You may not qualify if:

• Intention to quit marijuana or tobacco use in the next 30 days
• Self-reported illicit drug or heavy episodic alcohol use on \>20 days in the past month (excluding marijuana)
• Individuals who are pregnant or breastfeeding
• Positive saliva test for recent THC use
• Breath alcohol level above 0 at any session.
• Participants who exclusively roll their own tobacco cigarettes

Sponsors & Collaborators

• Brown University: lead
• National Institutes of Health (NIH): collaborator
• National Cancer Institute (NCI): collaborator

Study Sites (1)

Brown University School of Public Health

Providence, Rhode Island, 02903, United States

RECRUITING

MeSH Terms

Conditions

Marijuana Smoking; Tobacco Smoking

Condition Hierarchy (Ancestors)

Marijuana Use; Behavior; Smoking, Non-Tobacco Products; Smoking; Tobacco Use

Central Study Contacts

Elizabeth Aston, PhD

CONTACT

401-863-6668; elizabeth_aston@brown.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 4, 2026
• First Posted: February 9, 2026
• Study Start: February 17, 2026
• Primary Completion (Estimated): November 30, 2028
• Study Completion (Estimated): November 30, 2028
• Last Updated: March 4, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)