NCT07396948

Brief Summary

Patellofemoral pain syndrome (PFPS) is one of the most common causes of anterior knee pain in young and active individuals. PFPS is characterized by anterior knee pain. The treatment of choice is conservative management. However, there is still lack of widely accepted physiotherapeutic strategies aimed at alleviating patellofemoral pain. The outcomes of conservative treatment remain unsatisfactory. Therefore, the aim of this study was to compare the effectiveness of two physiotherapy protocols based on manual therapy and muscle training in the treatment of patellofemoral pain

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
46

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 22, 2026

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

February 2, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 9, 2026

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2026

Completed
Last Updated

February 9, 2026

Status Verified

January 1, 2026

Enrollment Period

1 month

First QC Date

February 2, 2026

Last Update Submit

February 2, 2026

Conditions

Keywords

patellofemoral pain syndrome

Outcome Measures

Primary Outcomes (2)

  • AKPS score

    6 weeks

  • VAS scale

    6 weeks

Study Arms (3)

training protocol

PLACEBO COMPARATOR

Training protocol with three exercises

Other: training protocol

medial patellar mobilization

ACTIVE COMPARATOR
Other: medial patellar mobilization

quadriceps muscle stretching

ACTIVE COMPARATOR
Other: quadriceps muscle stretching

Interventions

Patellar mobilization was carried out three times for 60 seconds each session \[19\]. The technique was performed by placing the therapist's thumbs on the lateral edge of the patella allowing a patellar glide in the medial and slightly caudal direction. The aim of this technique was to stretch the lateral patellar retinaculum

medial patellar mobilization

In order to perform this technique the patient was positioned prone on a treatment table (Figure 6). The non-stretched limb remained on the ground, flexed at the hip and knee. Moving this limb forward ensured proper aligment of the lumbar spine, while elevating the heel and placing it on the therapist's foot reduced tension in the hamstring group. Proper execution of the technique could be performed when the pelvis was aligned parallel to the surface, keeping the trunk and thigh of the stretched limb in one line. The therapist grasped by ipsilateral hand the distal third of the patient's lower leg and pulled the heel toward the buttock while by the contralateral hand stabilized the pelvis. The static position of stretching was maintained for 30 seconds in every repetition.

quadriceps muscle stretching

The training protocol included the following exercise: glute bridges, half squat, rear lunges, side walk with elastic band

training protocol

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Central Study Contacts

Piotr Łuczkiewicz, prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 2, 2026

First Posted

February 9, 2026

Study Start

January 22, 2026

Primary Completion

March 1, 2026

Study Completion

March 1, 2026

Last Updated

February 9, 2026

Record last verified: 2026-01