Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis

NCT07388992 | Recruiting

• 2 other identifiers: PR5030-1192025-A02511-48
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to investigate specific ambulation patterns characteristic of the quality of gait in people with MS (pwMS)

Conditions

Multiple Sclerosis; Healthy Adult

Outcome Measures

Primary Outcomes (1)

• description of ambulation pattern in controlled environment in people living with multiple sclerosis (pwMS) with different disease severities

  Measurement of daily life-like activity movements by Optical Motion Capture, pressure sensitive walkway and wearable sensors

  enrollment

Study Arms (2)

people living with Multiple Sclerosis

Healthy Adult

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with MS will be recruited from the CHU Lille. Patients will be informed of this study by the Investigator during routine follow-up visits. The Investigator will also connect with local patient organizations and share a flyer. This flyer will also be displayed within the Neurology and Neurological Rehabilitation departments of the hospital and diffused to the hospital staff.

You may qualify if:

• For people living with multiple sclerosis (pwMS):
• Signed informed consent and ability to comply with study and follow-up.
• Confirmed MS diagnosis according to McDonald criteria (2017)
• Expanded Disability Status Scale EDSS = 6
• Ability and willingness to participate in and comply with all study procedures defined in the protocol
• Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category
• For Healthy volunteers :
• Signed informed consent and ability to comply with study and follow-up.
• Ability and willingness to participate in and comply with all study procedures defined in the protocol
• Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category

You may not qualify if:

• For pwMS:
• Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
• Past or present pathology other than MS or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
• Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.
• For healthy volunteers (HV):
• Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
• Past or present pathology or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
• Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.

Sponsors & Collaborators

• SYSNAV: lead

Study Sites (1)

CHU Lille

Lille, France

RECRUITING

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Patrick Vermersch

  CHU Lille

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ferial Toumi

CONTACT

+33 2 78 00 10 98; ferial.toumi@sysnav.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 5, 2026
• Study Start: March 16, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: March 23, 2026

Record last verified: 2026-03

Locations

FR (1)